Twins methods quantitatively explore the genetic impact on children and adolescents brain gray matter volume

Abstract The gray matter volumes of 58 pairs of twins ranging in age from 12 to 18 were measured by MRI to explore the genetic and environmental impacts on gray matter volume in twin children and adolescents. By means of A/C/E structural equation modeling, it was found that the gray matter volume in...

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Autores principales:	Xiao-Lu Chen, Xiao-Wei Zhang, Xiao Hou, Xiao Li, Xing-Shun Ma, Xiao-Mei Hu, Hua-Qing Meng, Qian He, Lian-Sheng Zhao, Ying-Cheng Wang, Yi-Xiao Fu, Tao Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/3853b13f80624f048826b26b44dbdd0f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:3853b13f80624f048826b26b44dbdd0f2021-12-02T11:41:12ZTwins methods quantitatively explore the genetic impact on children and adolescents brain gray matter volume10.1038/s41598-017-03962-92045-2322https://doaj.org/article/3853b13f80624f048826b26b44dbdd0f2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-03962-9https://doaj.org/toc/2045-2322Abstract The gray matter volumes of 58 pairs of twins ranging in age from 12 to 18 were measured by MRI to explore the genetic and environmental impacts on gray matter volume in twin children and adolescents. By means of A/C/E structural equation modeling, it was found that the gray matter volume in children and adolescents was jointly affected by genetic (A: 0.89) and environmental factors while genetic factors play a greater role. The gray matter volume in frontal lobe, parietal lobe, occipital lobe and lateral temporal lobe was mainly affected by genetics (A: 0.7–0.89), where as the gray matter volume in medial temporal lobe and cingulate cortex was affected by both genetics and environment.Xiao-Lu ChenXiao-Wei ZhangXiao HouXiao LiXing-Shun MaXiao-Mei HuHua-Qing MengQian HeLian-Sheng ZhaoYing-Cheng WangYi-Xiao FuTao LiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-5 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Xiao-Lu Chen Xiao-Wei Zhang Xiao Hou Xiao Li Xing-Shun Ma Xiao-Mei Hu Hua-Qing Meng Qian He Lian-Sheng Zhao Ying-Cheng Wang Yi-Xiao Fu Tao Li Twins methods quantitatively explore the genetic impact on children and adolescents brain gray matter volume
description	Abstract The gray matter volumes of 58 pairs of twins ranging in age from 12 to 18 were measured by MRI to explore the genetic and environmental impacts on gray matter volume in twin children and adolescents. By means of A/C/E structural equation modeling, it was found that the gray matter volume in children and adolescents was jointly affected by genetic (A: 0.89) and environmental factors while genetic factors play a greater role. The gray matter volume in frontal lobe, parietal lobe, occipital lobe and lateral temporal lobe was mainly affected by genetics (A: 0.7–0.89), where as the gray matter volume in medial temporal lobe and cingulate cortex was affected by both genetics and environment.
format	article
author	Xiao-Lu Chen Xiao-Wei Zhang Xiao Hou Xiao Li Xing-Shun Ma Xiao-Mei Hu Hua-Qing Meng Qian He Lian-Sheng Zhao Ying-Cheng Wang Yi-Xiao Fu Tao Li
author_facet	Xiao-Lu Chen Xiao-Wei Zhang Xiao Hou Xiao Li Xing-Shun Ma Xiao-Mei Hu Hua-Qing Meng Qian He Lian-Sheng Zhao Ying-Cheng Wang Yi-Xiao Fu Tao Li
author_sort	Xiao-Lu Chen
title	Twins methods quantitatively explore the genetic impact on children and adolescents brain gray matter volume
title_short	Twins methods quantitatively explore the genetic impact on children and adolescents brain gray matter volume
title_full	Twins methods quantitatively explore the genetic impact on children and adolescents brain gray matter volume
title_fullStr	Twins methods quantitatively explore the genetic impact on children and adolescents brain gray matter volume
title_full_unstemmed	Twins methods quantitatively explore the genetic impact on children and adolescents brain gray matter volume
title_sort	twins methods quantitatively explore the genetic impact on children and adolescents brain gray matter volume
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/3853b13f80624f048826b26b44dbdd0f
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Twins methods quantitatively explore the genetic impact on children and adolescents brain gray matter volume

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