Prevalence of uterine rupture among women with one prior low transverse cesarean and women with unscarred uterus undergoing labor induction with PGE2: A systematic review and meta-analysis.

<h4>Background</h4>As uterine rupture may affect as many as 11/1000 women with 1 prior cesarean birth and 5/10.000 women with unscarred uterus undergoing labor induction, we intended to estimate the prevalence of such rare outcome when PGE2 is used for cervical ripening and labor inducti...

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Autores principales: Giuseppe Chiossi, Roberto D'Amico, Anna L Tramontano, Veronica Sampogna, Viola Laghi, Fabio Facchinetti
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Publicado: Public Library of Science (PLoS) 2021
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spelling oai:doaj.org-article:38544400b6cc4b1f94cb3bc5959736332021-12-02T20:09:39ZPrevalence of uterine rupture among women with one prior low transverse cesarean and women with unscarred uterus undergoing labor induction with PGE2: A systematic review and meta-analysis.1932-620310.1371/journal.pone.0253957https://doaj.org/article/38544400b6cc4b1f94cb3bc5959736332021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253957https://doaj.org/toc/1932-6203<h4>Background</h4>As uterine rupture may affect as many as 11/1000 women with 1 prior cesarean birth and 5/10.000 women with unscarred uterus undergoing labor induction, we intended to estimate the prevalence of such rare outcome when PGE2 is used for cervical ripening and labor induction.<h4>Methods</h4>We searched MEDLINE, ClinicalTrials.gov and the Cochrane library up to September 1st 2020. Retrospective and prospective cohort studies, as well as randomized controlled trials (RCTs) on singleton viable pregnancies receiving PGE2 for cervical ripening and labor induction were reviewed. Prevalence of uterine rupture was meta-analyzed with Freeman-Tukey double arcsine transformation among women with 1 prior low transverse cesarean section and women with unscarred uterus.<h4>Results</h4>We reviewed 956 full text articles to include 69 studies. The pooled prevalence rate of uterine rupture is estimated to range between 2 and 9 out of 1000 women with 1 prior low transverse cesarean (5/1000; 95%CI 2-9/1000, 122/9000). The prevalence of uterine rupture among women with unscarred uterus is extremely low, reaching at most 0.7/100.000 (<1/100.000.000; 95%CI <1/100.000.000-0.7/100.000, 8/17.684).<h4>Conclusions</h4>Uterine rupture is a rare event during cervical ripening and labor induction with PGE2.Giuseppe ChiossiRoberto D'AmicoAnna L TramontanoVeronica SampognaViola LaghiFabio FacchinettiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 7, p e0253957 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Giuseppe Chiossi
Roberto D'Amico
Anna L Tramontano
Veronica Sampogna
Viola Laghi
Fabio Facchinetti
Prevalence of uterine rupture among women with one prior low transverse cesarean and women with unscarred uterus undergoing labor induction with PGE2: A systematic review and meta-analysis.
description <h4>Background</h4>As uterine rupture may affect as many as 11/1000 women with 1 prior cesarean birth and 5/10.000 women with unscarred uterus undergoing labor induction, we intended to estimate the prevalence of such rare outcome when PGE2 is used for cervical ripening and labor induction.<h4>Methods</h4>We searched MEDLINE, ClinicalTrials.gov and the Cochrane library up to September 1st 2020. Retrospective and prospective cohort studies, as well as randomized controlled trials (RCTs) on singleton viable pregnancies receiving PGE2 for cervical ripening and labor induction were reviewed. Prevalence of uterine rupture was meta-analyzed with Freeman-Tukey double arcsine transformation among women with 1 prior low transverse cesarean section and women with unscarred uterus.<h4>Results</h4>We reviewed 956 full text articles to include 69 studies. The pooled prevalence rate of uterine rupture is estimated to range between 2 and 9 out of 1000 women with 1 prior low transverse cesarean (5/1000; 95%CI 2-9/1000, 122/9000). The prevalence of uterine rupture among women with unscarred uterus is extremely low, reaching at most 0.7/100.000 (<1/100.000.000; 95%CI <1/100.000.000-0.7/100.000, 8/17.684).<h4>Conclusions</h4>Uterine rupture is a rare event during cervical ripening and labor induction with PGE2.
format article
author Giuseppe Chiossi
Roberto D'Amico
Anna L Tramontano
Veronica Sampogna
Viola Laghi
Fabio Facchinetti
author_facet Giuseppe Chiossi
Roberto D'Amico
Anna L Tramontano
Veronica Sampogna
Viola Laghi
Fabio Facchinetti
author_sort Giuseppe Chiossi
title Prevalence of uterine rupture among women with one prior low transverse cesarean and women with unscarred uterus undergoing labor induction with PGE2: A systematic review and meta-analysis.
title_short Prevalence of uterine rupture among women with one prior low transverse cesarean and women with unscarred uterus undergoing labor induction with PGE2: A systematic review and meta-analysis.
title_full Prevalence of uterine rupture among women with one prior low transverse cesarean and women with unscarred uterus undergoing labor induction with PGE2: A systematic review and meta-analysis.
title_fullStr Prevalence of uterine rupture among women with one prior low transverse cesarean and women with unscarred uterus undergoing labor induction with PGE2: A systematic review and meta-analysis.
title_full_unstemmed Prevalence of uterine rupture among women with one prior low transverse cesarean and women with unscarred uterus undergoing labor induction with PGE2: A systematic review and meta-analysis.
title_sort prevalence of uterine rupture among women with one prior low transverse cesarean and women with unscarred uterus undergoing labor induction with pge2: a systematic review and meta-analysis.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/38544400b6cc4b1f94cb3bc595973633
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