Down-regulation of long non-coding RNA HOTAIR sensitizes breast cancer to trastuzumab

Down-regulation of long non-coding RNA HOTAIR sensitizes breast cancer to trastuzumab

Abstract This study aimed to investigate the roles and possible molecular mechanisms of long non-coding RNA HOTAIR in regulating resistance to trastuzumab in breast cancer. Trastuzumab-resistant breast cancer cell line SK-BR-3-TR was assayed for the expression of HOX antisense intergenic RNA (HOTAIR...

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Bibliographic Details
Main Authors: Tianwen Chen, Zeming Liu, Wen Zeng, Tao Huang
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/3855a6244f2848df99e4664ad40a9a22
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