Down-regulation of long non-coding RNA HOTAIR sensitizes breast cancer to trastuzumab

Down-regulation of long non-coding RNA HOTAIR sensitizes breast cancer to trastuzumab

Abstract This study aimed to investigate the roles and possible molecular mechanisms of long non-coding RNA HOTAIR in regulating resistance to trastuzumab in breast cancer. Trastuzumab-resistant breast cancer cell line SK-BR-3-TR was assayed for the expression of HOX antisense intergenic RNA (HOTAIR...

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Autores principales: Tianwen Chen, Zeming Liu, Wen Zeng, Tao Huang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3855a6244f2848df99e4664ad40a9a22
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