Potential drug interactions and inappropriate medications prescribed for primary health care users

Objectives: To analyze potential pharmacological interactions and drugs potentially inappropriate for the elderly in users of primary care of the Unified Health System. Methods: This is a cross-sectional study with individuals aged 18 years or over, who were approached at the health facilities of t...

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Autores principales:	Rafaela S. ROCHA, Luanna G. SILVA, Máyra R. FERNANDES, Roberta C. FIGUEIREDO, André O. BALDONI
Formato:	article
Lenguaje:	EN PT
Publicado:	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde 2020
Materias:	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/385885b7e3ca4cbcbc7b2d66bff24cd1
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spelling	oai:doaj.org-article:385885b7e3ca4cbcbc7b2d66bff24cd12021-11-28T02:45:00ZPotential drug interactions and inappropriate medications prescribed for primary health care users10.30968/rbfhss.2020.112.03652179-59242316-7750https://doaj.org/article/385885b7e3ca4cbcbc7b2d66bff24cd12020-07-01T00:00:00Zhttps://www.rbfhss.org.br/sbrafh/article/view/365https://doaj.org/toc/2179-5924https://doaj.org/toc/2316-7750 Objectives: To analyze potential pharmacological interactions and drugs potentially inappropriate for the elderly in users of primary care of the Unified Health System. Methods: This is a cross-sectional study with individuals aged 18 years or over, who were approached at the health facilities of the city of Divinópolis, MG, at which time a home visit was scheduled. A structured questionnaire on drug use was applied and drug interactions were analyzed in Drugs.com® sources, Micromedex®, bulletin of the Brazilian Health Regulatory Agency (ANVISA). Only the frequencies of serious interactions were analyzed. Potentially inappropriate drugs for elderly people (MPI) were identified by the Beers Criterion (2015) and the Brazilian Consensus on Potentially Inappropriate Medications for the Elderly (2016). The Mann-Whitney test was performed to compare the medians of the analyzed variables. Results: Among the study participants, 55% were elderly. Comparing them with the adult population, it was observed that the number of medications and potential drug interactions were significantly higher (p <0.05) among patients 60 years of age or older. Considering only the elderly, 77.3% used at least one MPI, according to the Beers Criterion. Conclusion: It was found that the vast majority of primary care users use at least one inappropriate drug and, when compared to adults, are more exposed to polypharmacy and potential drug interactions. Rafaela S. ROCHALuanna G. SILVAMáyra R. FERNANDESRoberta C. FIGUEIREDOAndré O. BALDONISociedade Brasileira de Farmácia Hospitalar e Serviços de SaúdearticlePublic aspects of medicineRA1-1270Pharmacy and materia medicaRS1-441Therapeutics. PharmacologyRM1-950ENPTRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 11, Iss 2 (2020)
institution	DOAJ
collection	DOAJ
language	EN PT
topic	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
spellingShingle	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950 Rafaela S. ROCHA Luanna G. SILVA Máyra R. FERNANDES Roberta C. FIGUEIREDO André O. BALDONI Potential drug interactions and inappropriate medications prescribed for primary health care users
description	Objectives: To analyze potential pharmacological interactions and drugs potentially inappropriate for the elderly in users of primary care of the Unified Health System. Methods: This is a cross-sectional study with individuals aged 18 years or over, who were approached at the health facilities of the city of Divinópolis, MG, at which time a home visit was scheduled. A structured questionnaire on drug use was applied and drug interactions were analyzed in Drugs.com® sources, Micromedex®, bulletin of the Brazilian Health Regulatory Agency (ANVISA). Only the frequencies of serious interactions were analyzed. Potentially inappropriate drugs for elderly people (MPI) were identified by the Beers Criterion (2015) and the Brazilian Consensus on Potentially Inappropriate Medications for the Elderly (2016). The Mann-Whitney test was performed to compare the medians of the analyzed variables. Results: Among the study participants, 55% were elderly. Comparing them with the adult population, it was observed that the number of medications and potential drug interactions were significantly higher (p <0.05) among patients 60 years of age or older. Considering only the elderly, 77.3% used at least one MPI, according to the Beers Criterion. Conclusion: It was found that the vast majority of primary care users use at least one inappropriate drug and, when compared to adults, are more exposed to polypharmacy and potential drug interactions.
format	article
author	Rafaela S. ROCHA Luanna G. SILVA Máyra R. FERNANDES Roberta C. FIGUEIREDO André O. BALDONI
author_facet	Rafaela S. ROCHA Luanna G. SILVA Máyra R. FERNANDES Roberta C. FIGUEIREDO André O. BALDONI
author_sort	Rafaela S. ROCHA
title	Potential drug interactions and inappropriate medications prescribed for primary health care users
title_short	Potential drug interactions and inappropriate medications prescribed for primary health care users
title_full	Potential drug interactions and inappropriate medications prescribed for primary health care users
title_fullStr	Potential drug interactions and inappropriate medications prescribed for primary health care users
title_full_unstemmed	Potential drug interactions and inappropriate medications prescribed for primary health care users
title_sort	potential drug interactions and inappropriate medications prescribed for primary health care users
publisher	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
publishDate	2020
url	https://doaj.org/article/385885b7e3ca4cbcbc7b2d66bff24cd1
work_keys_str_mv	AT rafaelasrocha potentialdruginteractionsandinappropriatemedicationsprescribedforprimaryhealthcareusers AT luannagsilva potentialdruginteractionsandinappropriatemedicationsprescribedforprimaryhealthcareusers AT mayrarfernandes potentialdruginteractionsandinappropriatemedicationsprescribedforprimaryhealthcareusers AT robertacfigueiredo potentialdruginteractionsandinappropriatemedicationsprescribedforprimaryhealthcareusers AT andreobaldoni potentialdruginteractionsandinappropriatemedicationsprescribedforprimaryhealthcareusers
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Potential drug interactions and inappropriate medications prescribed for primary health care users

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