Simultaneous hepatosplenic T-cell lymphoma and myelofibrosis

Hepatosplenic T-cell lymphoma (HSTL) is a rare T-cell neoplasm of the lymphoid system. This type of lymphoma is characterized by sinusoidal infiltration of spleen, liver, bone marrow and lymph nodes by neoplastic lymphocytes. Here, we discuss a patient who had a left axillary lymph node biopsy with...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ali M Gabali, Tarek Jazaerly, Chung-Che Jeff Chang, Ronald Cleveland, Lawrence Kass
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2014
Materias:	bone marrow cd3 jak2 liver t-cell Medicine R
Acceso en línea:	https://doaj.org/article/3875638bb30d4364ad7e3692e18ae8c0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3875638bb30d4364ad7e3692e18ae8c0
record_format	dspace
spelling	oai:doaj.org-article:3875638bb30d4364ad7e3692e18ae8c02021-12-02T17:05:52ZSimultaneous hepatosplenic T-cell lymphoma and myelofibrosis2231-07702249-446410.4103/2231-0770.130343https://doaj.org/article/3875638bb30d4364ad7e3692e18ae8c02014-04-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.130343https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Hepatosplenic T-cell lymphoma (HSTL) is a rare T-cell neoplasm of the lymphoid system. This type of lymphoma is characterized by sinusoidal infiltration of spleen, liver, bone marrow and lymph nodes by neoplastic lymphocytes. Here, we discuss a patient who had a left axillary lymph node biopsy with characteristic histological and immunohistochemical features of HSTL. In addition, infiltrating neoplastic T-cells and simultaneous characteristic features of myelofibrosis (MF) were also present in the bone marrow biopsy specimen. In contrast to secondary MF, primary MF is a progressive disease and may significantly affect the prognosis of coexisting HSTL. There are few reports in the literature talking about mild bone marrow fibrosis in association with T cell lymphoma, however marked increase in bone marrow fibrosis and HSTL never being reported. This case is shedding light on HSTL and marked increase in bone marrow fibrosis.Ali M GabaliTarek JazaerlyChung-Che Jeff ChangRonald ClevelandLawrence KassThieme Medical and Scientific Publishers Pvt. Ltd.articlebone marrowcd3jak2livert-cellMedicineRENAvicenna Journal of Medicine, Vol 04, Iss 02, Pp 34-36 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	bone marrow cd3 jak2 liver t-cell Medicine R
spellingShingle	bone marrow cd3 jak2 liver t-cell Medicine R Ali M Gabali Tarek Jazaerly Chung-Che Jeff Chang Ronald Cleveland Lawrence Kass Simultaneous hepatosplenic T-cell lymphoma and myelofibrosis
description	Hepatosplenic T-cell lymphoma (HSTL) is a rare T-cell neoplasm of the lymphoid system. This type of lymphoma is characterized by sinusoidal infiltration of spleen, liver, bone marrow and lymph nodes by neoplastic lymphocytes. Here, we discuss a patient who had a left axillary lymph node biopsy with characteristic histological and immunohistochemical features of HSTL. In addition, infiltrating neoplastic T-cells and simultaneous characteristic features of myelofibrosis (MF) were also present in the bone marrow biopsy specimen. In contrast to secondary MF, primary MF is a progressive disease and may significantly affect the prognosis of coexisting HSTL. There are few reports in the literature talking about mild bone marrow fibrosis in association with T cell lymphoma, however marked increase in bone marrow fibrosis and HSTL never being reported. This case is shedding light on HSTL and marked increase in bone marrow fibrosis.
format	article
author	Ali M Gabali Tarek Jazaerly Chung-Che Jeff Chang Ronald Cleveland Lawrence Kass
author_facet	Ali M Gabali Tarek Jazaerly Chung-Che Jeff Chang Ronald Cleveland Lawrence Kass
author_sort	Ali M Gabali
title	Simultaneous hepatosplenic T-cell lymphoma and myelofibrosis
title_short	Simultaneous hepatosplenic T-cell lymphoma and myelofibrosis
title_full	Simultaneous hepatosplenic T-cell lymphoma and myelofibrosis
title_fullStr	Simultaneous hepatosplenic T-cell lymphoma and myelofibrosis
title_full_unstemmed	Simultaneous hepatosplenic T-cell lymphoma and myelofibrosis
title_sort	simultaneous hepatosplenic t-cell lymphoma and myelofibrosis
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2014
url	https://doaj.org/article/3875638bb30d4364ad7e3692e18ae8c0
work_keys_str_mv	AT alimgabali simultaneoushepatosplenictcelllymphomaandmyelofibrosis AT tarekjazaerly simultaneoushepatosplenictcelllymphomaandmyelofibrosis AT chungchejeffchang simultaneoushepatosplenictcelllymphomaandmyelofibrosis AT ronaldcleveland simultaneoushepatosplenictcelllymphomaandmyelofibrosis AT lawrencekass simultaneoushepatosplenictcelllymphomaandmyelofibrosis
_version_	1718381785405980672

Simultaneous hepatosplenic T-cell lymphoma and myelofibrosis

Ejemplares similares