Insulin Autoimmune Syndrome as Part of Pre-Clinical LADA

Edyta Sutkowska,1 Malgorzata Ostrowska,2 Magdalena Sutkowska3 1Medical Division, Department and Division of Medical Rehabilitation, Wroclaw Medical University, Wroclaw, Poland; 2Clinical Department of Nephrology and Dialysis Station, Karol Marcinkowski University Hospital, Zielona Gora, Poland; 3Med...

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Autores principales: Sutkowska E, Ostrowska M, Sutkowska M
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Publicado: Dove Medical Press 2021
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spelling oai:doaj.org-article:38768e12925f4b7090e39d1cc6a819c62021-12-02T14:22:43ZInsulin Autoimmune Syndrome as Part of Pre-Clinical LADA1178-7007https://doaj.org/article/38768e12925f4b7090e39d1cc6a819c62021-04-01T00:00:00Zhttps://www.dovepress.com/insulin-autoimmune-syndrome-as-part-of-pre-clinical-lada-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Edyta Sutkowska,1 Malgorzata Ostrowska,2 Magdalena Sutkowska3 1Medical Division, Department and Division of Medical Rehabilitation, Wroclaw Medical University, Wroclaw, Poland; 2Clinical Department of Nephrology and Dialysis Station, Karol Marcinkowski University Hospital, Zielona Gora, Poland; 3Medical Division, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Edyta SutkowskaDepartment and Division of Medical Rehabilitation, Wroclaw Medical University, Borowska 213, Wroclaw, 50-556, PolandTel +48 71 734 32 20Email edyta.sutkowska@umed.wroc.plAbstract: Hypoglycemia presents relatively typical symptoms. However, when it occurs spontaneously – like in insulin autoimmune syndrome – it is difficult to perform scheduled biochemical tests at the laboratory. The study presents the case of a 31-year-old Caucasian female whose recurrent hypoglycemia symptoms were the reason for further diagnostics. The final results revealed a positive test for insulin autoantibody and glutamic acid decarboxylase autoantibody. Therefore, not only the potential causes of hypoglycemia but also an active autoimmune process typical for latent autoimmune diabetes in adults were confirmed. It was concluded that autoimmune hypoglycemia can be a part of the autoimmune process associated with diabetes and pre-diabetes in adults.Keywords: autoimmune hypoglycemia, latent autoimmune diabetes, insulin autoantibodies, pre-clinical diabetesSutkowska EOstrowska MSutkowska MDove Medical Pressarticleautoimmune hypoglycemialatent autoimmune diabetesinsulin autoantibodiespre-clinical diabetesSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 14, Pp 1557-1561 (2021)
institution DOAJ
collection DOAJ
language EN
topic autoimmune hypoglycemia
latent autoimmune diabetes
insulin autoantibodies
pre-clinical diabetes
Specialties of internal medicine
RC581-951
spellingShingle autoimmune hypoglycemia
latent autoimmune diabetes
insulin autoantibodies
pre-clinical diabetes
Specialties of internal medicine
RC581-951
Sutkowska E
Ostrowska M
Sutkowska M
Insulin Autoimmune Syndrome as Part of Pre-Clinical LADA
description Edyta Sutkowska,1 Malgorzata Ostrowska,2 Magdalena Sutkowska3 1Medical Division, Department and Division of Medical Rehabilitation, Wroclaw Medical University, Wroclaw, Poland; 2Clinical Department of Nephrology and Dialysis Station, Karol Marcinkowski University Hospital, Zielona Gora, Poland; 3Medical Division, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Edyta SutkowskaDepartment and Division of Medical Rehabilitation, Wroclaw Medical University, Borowska 213, Wroclaw, 50-556, PolandTel +48 71 734 32 20Email edyta.sutkowska@umed.wroc.plAbstract: Hypoglycemia presents relatively typical symptoms. However, when it occurs spontaneously – like in insulin autoimmune syndrome – it is difficult to perform scheduled biochemical tests at the laboratory. The study presents the case of a 31-year-old Caucasian female whose recurrent hypoglycemia symptoms were the reason for further diagnostics. The final results revealed a positive test for insulin autoantibody and glutamic acid decarboxylase autoantibody. Therefore, not only the potential causes of hypoglycemia but also an active autoimmune process typical for latent autoimmune diabetes in adults were confirmed. It was concluded that autoimmune hypoglycemia can be a part of the autoimmune process associated with diabetes and pre-diabetes in adults.Keywords: autoimmune hypoglycemia, latent autoimmune diabetes, insulin autoantibodies, pre-clinical diabetes
format article
author Sutkowska E
Ostrowska M
Sutkowska M
author_facet Sutkowska E
Ostrowska M
Sutkowska M
author_sort Sutkowska E
title Insulin Autoimmune Syndrome as Part of Pre-Clinical LADA
title_short Insulin Autoimmune Syndrome as Part of Pre-Clinical LADA
title_full Insulin Autoimmune Syndrome as Part of Pre-Clinical LADA
title_fullStr Insulin Autoimmune Syndrome as Part of Pre-Clinical LADA
title_full_unstemmed Insulin Autoimmune Syndrome as Part of Pre-Clinical LADA
title_sort insulin autoimmune syndrome as part of pre-clinical lada
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/38768e12925f4b7090e39d1cc6a819c6
work_keys_str_mv AT sutkowskae insulinautoimmunesyndromeaspartofpreclinicallada
AT ostrowskam insulinautoimmunesyndromeaspartofpreclinicallada
AT sutkowskam insulinautoimmunesyndromeaspartofpreclinicallada
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