Crosstalk between MSH2–MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair
The expansion of trinucleotide repeats can have detrimental effects and give rise to a range of human diseases. Here the authors report that the mismatch repair and the base excision repair machinery can operate together to promote expansion during lesion removal.
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| Autores principales: | , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/3879ba8a8aee40aca671630c5cc0af1e |
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