Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection from other inputs.
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Nature Portfolio
2018
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oai:doaj.org-article:387d2ac97fcc4d5db68d5938d05e99052021-12-02T16:56:58ZAutapses enhance bursting and coincidence detection in neocortical pyramidal cells10.1038/s41467-018-07317-42041-1723https://doaj.org/article/387d2ac97fcc4d5db68d5938d05e99052018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07317-4https://doaj.org/toc/2041-1723While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection from other inputs.Luping YinRui ZhengWei KeQuansheng HeYi ZhangJunlong LiBo WangZhen MiYue-sheng LongMalte J. RaschTianfu LiGuoming LuanYousheng ShuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Luping Yin Rui Zheng Wei Ke Quansheng He Yi Zhang Junlong Li Bo Wang Zhen Mi Yue-sheng Long Malte J. Rasch Tianfu Li Guoming Luan Yousheng Shu Autapses enhance bursting and coincidence detection in neocortical pyramidal cells |
description |
While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection from other inputs. |
format |
article |
author |
Luping Yin Rui Zheng Wei Ke Quansheng He Yi Zhang Junlong Li Bo Wang Zhen Mi Yue-sheng Long Malte J. Rasch Tianfu Li Guoming Luan Yousheng Shu |
author_facet |
Luping Yin Rui Zheng Wei Ke Quansheng He Yi Zhang Junlong Li Bo Wang Zhen Mi Yue-sheng Long Malte J. Rasch Tianfu Li Guoming Luan Yousheng Shu |
author_sort |
Luping Yin |
title |
Autapses enhance bursting and coincidence detection in neocortical pyramidal cells |
title_short |
Autapses enhance bursting and coincidence detection in neocortical pyramidal cells |
title_full |
Autapses enhance bursting and coincidence detection in neocortical pyramidal cells |
title_fullStr |
Autapses enhance bursting and coincidence detection in neocortical pyramidal cells |
title_full_unstemmed |
Autapses enhance bursting and coincidence detection in neocortical pyramidal cells |
title_sort |
autapses enhance bursting and coincidence detection in neocortical pyramidal cells |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/387d2ac97fcc4d5db68d5938d05e9905 |
work_keys_str_mv |
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