Autapses enhance bursting and coincidence detection in neocortical pyramidal cells

While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection from other inputs.

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Autores principales: Luping Yin, Rui Zheng, Wei Ke, Quansheng He, Yi Zhang, Junlong Li, Bo Wang, Zhen Mi, Yue-sheng Long, Malte J. Rasch, Tianfu Li, Guoming Luan, Yousheng Shu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/387d2ac97fcc4d5db68d5938d05e9905
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spelling oai:doaj.org-article:387d2ac97fcc4d5db68d5938d05e99052021-12-02T16:56:58ZAutapses enhance bursting and coincidence detection in neocortical pyramidal cells10.1038/s41467-018-07317-42041-1723https://doaj.org/article/387d2ac97fcc4d5db68d5938d05e99052018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07317-4https://doaj.org/toc/2041-1723While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection from other inputs.Luping YinRui ZhengWei KeQuansheng HeYi ZhangJunlong LiBo WangZhen MiYue-sheng LongMalte J. RaschTianfu LiGuoming LuanYousheng ShuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Luping Yin
Rui Zheng
Wei Ke
Quansheng He
Yi Zhang
Junlong Li
Bo Wang
Zhen Mi
Yue-sheng Long
Malte J. Rasch
Tianfu Li
Guoming Luan
Yousheng Shu
Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
description While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection from other inputs.
format article
author Luping Yin
Rui Zheng
Wei Ke
Quansheng He
Yi Zhang
Junlong Li
Bo Wang
Zhen Mi
Yue-sheng Long
Malte J. Rasch
Tianfu Li
Guoming Luan
Yousheng Shu
author_facet Luping Yin
Rui Zheng
Wei Ke
Quansheng He
Yi Zhang
Junlong Li
Bo Wang
Zhen Mi
Yue-sheng Long
Malte J. Rasch
Tianfu Li
Guoming Luan
Yousheng Shu
author_sort Luping Yin
title Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
title_short Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
title_full Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
title_fullStr Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
title_full_unstemmed Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
title_sort autapses enhance bursting and coincidence detection in neocortical pyramidal cells
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/387d2ac97fcc4d5db68d5938d05e9905
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