Autapses enhance bursting and coincidence detection in neocortical pyramidal cells

While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection from other inputs.

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Bibliographic Details
Main Authors:	Luping Yin, Rui Zheng, Wei Ke, Quansheng He, Yi Zhang, Junlong Li, Bo Wang, Zhen Mi, Yue-sheng Long, Malte J. Rasch, Tianfu Li, Guoming Luan, Yousheng Shu
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/387d2ac97fcc4d5db68d5938d05e9905
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spelling	oai:doaj.org-article:387d2ac97fcc4d5db68d5938d05e99052021-12-02T16:56:58ZAutapses enhance bursting and coincidence detection in neocortical pyramidal cells10.1038/s41467-018-07317-42041-1723https://doaj.org/article/387d2ac97fcc4d5db68d5938d05e99052018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07317-4https://doaj.org/toc/2041-1723While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection from other inputs.Luping YinRui ZhengWei KeQuansheng HeYi ZhangJunlong LiBo WangZhen MiYue-sheng LongMalte J. RaschTianfu LiGuoming LuanYousheng ShuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Luping Yin Rui Zheng Wei Ke Quansheng He Yi Zhang Junlong Li Bo Wang Zhen Mi Yue-sheng Long Malte J. Rasch Tianfu Li Guoming Luan Yousheng Shu Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
description	While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection from other inputs.
format	article
author	Luping Yin Rui Zheng Wei Ke Quansheng He Yi Zhang Junlong Li Bo Wang Zhen Mi Yue-sheng Long Malte J. Rasch Tianfu Li Guoming Luan Yousheng Shu
author_facet	Luping Yin Rui Zheng Wei Ke Quansheng He Yi Zhang Junlong Li Bo Wang Zhen Mi Yue-sheng Long Malte J. Rasch Tianfu Li Guoming Luan Yousheng Shu
author_sort	Luping Yin
title	Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
title_short	Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
title_full	Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
title_fullStr	Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
title_full_unstemmed	Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
title_sort	autapses enhance bursting and coincidence detection in neocortical pyramidal cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/387d2ac97fcc4d5db68d5938d05e9905
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Autapses enhance bursting and coincidence detection in neocortical pyramidal cells

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