Lipoxin A₄ prevents the progression of de novo and established endometriosis in a mouse model by attenuating prostaglandin E₂ production and estrogen signaling.

Endometriosis, a leading cause of pelvic pain and infertility, is characterized by ectopic growth of endometrial-like tissue and affects approximately 176 million women worldwide. The pathophysiology involves inflammatory and angiogenic mediators as well as estrogen-mediated signaling and novel, imp...

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Autores principales: Rajesh Kumar, Anne-Catherine Clerc, Ilaria Gori, Ronan Russell, Chiara Pellegrini, Lerisa Govender, Jean-Christophe Wyss, Dela Golshayan, Geraldine O Canny
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/38800685721149aeb2a7655c6cd80daa
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