A single protofilament is sufficient to support unidirectional walking of dynein and kinesin.
Cytoplasmic dynein and kinesin are two-headed microtubule motor proteins that move in opposite directions on microtubules. It is known that kinesin steps by a 'hand-over-hand' mechanism, but it is unclear by which mechanism dynein steps. Because dynein has a completely different structure...
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Autores principales: | Keitaro Shibata, Michi Miura, Yuta Watanabe, Kei Saito, Atsuko Nishimura, Ken'ya Furuta, Yoko Y Toyoshima |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/3897024a66f24558bfdf1de381e27b14 |
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