AMPK Activity: A Primary Target for Diabetes Prevention with Therapeutic Phytochemicals

Diabetes is a metabolic syndrome characterized by inadequate blood glucose control and is associated with reduced quality of life and various complications, significantly shortening life expectancy. Natural phytochemicals found in plants have been traditionally used as medicines for the prevention o...

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Autores principales:	Min-Yu Chung, Hyo-Kyoung Choi, Jin-Taek Hwang
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	diabetes AMP-activated protein kinase medicinal plants ingredient Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/3898dee4efc54e9fbed233d36b822fc6
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spelling	oai:doaj.org-article:3898dee4efc54e9fbed233d36b822fc62021-11-25T18:36:24ZAMPK Activity: A Primary Target for Diabetes Prevention with Therapeutic Phytochemicals10.3390/nu131140502072-6643https://doaj.org/article/3898dee4efc54e9fbed233d36b822fc62021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/4050https://doaj.org/toc/2072-6643Diabetes is a metabolic syndrome characterized by inadequate blood glucose control and is associated with reduced quality of life and various complications, significantly shortening life expectancy. Natural phytochemicals found in plants have been traditionally used as medicines for the prevention of chronic diseases including diabetes in East Asia since ancient times. Many of these phytochemicals have been characterized as having few side effects, and scientific research into the mechanisms of action responsible has accumulated mounting evidence for their efficacy. These compounds, which may help to prevent metabolic syndrome disorders including diabetes, act through relevant intracellular signaling pathways. In this review, we examine the anti-diabetic efficacy of several compounds and extracts derived from medicinal plants, with a focus on AMP-activated protein kinase (AMPK) activity.Min-Yu ChungHyo-Kyoung ChoiJin-Taek HwangMDPI AGarticlediabetesAMP-activated protein kinasemedicinal plantsingredientNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 4050, p 4050 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	diabetes AMP-activated protein kinase medicinal plants ingredient Nutrition. Foods and food supply TX341-641
spellingShingle	diabetes AMP-activated protein kinase medicinal plants ingredient Nutrition. Foods and food supply TX341-641 Min-Yu Chung Hyo-Kyoung Choi Jin-Taek Hwang AMPK Activity: A Primary Target for Diabetes Prevention with Therapeutic Phytochemicals
description	Diabetes is a metabolic syndrome characterized by inadequate blood glucose control and is associated with reduced quality of life and various complications, significantly shortening life expectancy. Natural phytochemicals found in plants have been traditionally used as medicines for the prevention of chronic diseases including diabetes in East Asia since ancient times. Many of these phytochemicals have been characterized as having few side effects, and scientific research into the mechanisms of action responsible has accumulated mounting evidence for their efficacy. These compounds, which may help to prevent metabolic syndrome disorders including diabetes, act through relevant intracellular signaling pathways. In this review, we examine the anti-diabetic efficacy of several compounds and extracts derived from medicinal plants, with a focus on AMP-activated protein kinase (AMPK) activity.
format	article
author	Min-Yu Chung Hyo-Kyoung Choi Jin-Taek Hwang
author_facet	Min-Yu Chung Hyo-Kyoung Choi Jin-Taek Hwang
author_sort	Min-Yu Chung
title	AMPK Activity: A Primary Target for Diabetes Prevention with Therapeutic Phytochemicals
title_short	AMPK Activity: A Primary Target for Diabetes Prevention with Therapeutic Phytochemicals
title_full	AMPK Activity: A Primary Target for Diabetes Prevention with Therapeutic Phytochemicals
title_fullStr	AMPK Activity: A Primary Target for Diabetes Prevention with Therapeutic Phytochemicals
title_full_unstemmed	AMPK Activity: A Primary Target for Diabetes Prevention with Therapeutic Phytochemicals
title_sort	ampk activity: a primary target for diabetes prevention with therapeutic phytochemicals
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/3898dee4efc54e9fbed233d36b822fc6
work_keys_str_mv	AT minyuchung ampkactivityaprimarytargetfordiabetespreventionwiththerapeuticphytochemicals AT hyokyoungchoi ampkactivityaprimarytargetfordiabetespreventionwiththerapeuticphytochemicals AT jintaekhwang ampkactivityaprimarytargetfordiabetespreventionwiththerapeuticphytochemicals
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AMPK Activity: A Primary Target for Diabetes Prevention with Therapeutic Phytochemicals

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