Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures

While breast cancer incidence in the Asia Pacific region is rising, the molecular basis remains poorly characterized. Here the authors perform genomic screening of 187 Korean breast cancer patients and find differences in molecular subtype distribution, mutation pattern and prevalence, and gene expr...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Zhengyan Kan, Ying Ding, Jinho Kim, Hae Hyun Jung, Woosung Chung, Samir Lal, Soonweng Cho, Julio Fernandez-Banet, Se Kyung Lee, Seok Won Kim, Jeong Eon Lee, Yoon-La Choi, Shibing Deng, Ji-Yeon Kim, Jin Seok Ahn, Ying Sha, Xinmeng Jasmine Mu, Jae-Yong Nam, Young-Hyuck Im, Soohyeon Lee, Woong-Yang Park, Seok Jin Nam, Yeon Hee Park
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/389b15f6241d433099ba837bc4efcf72
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:389b15f6241d433099ba837bc4efcf72
record_format	dspace
spelling	oai:doaj.org-article:389b15f6241d433099ba837bc4efcf722021-12-02T17:31:14ZMulti-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures10.1038/s41467-018-04129-42041-1723https://doaj.org/article/389b15f6241d433099ba837bc4efcf722018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04129-4https://doaj.org/toc/2041-1723While breast cancer incidence in the Asia Pacific region is rising, the molecular basis remains poorly characterized. Here the authors perform genomic screening of 187 Korean breast cancer patients and find differences in molecular subtype distribution, mutation pattern and prevalence, and gene expression signature when compared to TCGA.Zhengyan KanYing DingJinho KimHae Hyun JungWoosung ChungSamir LalSoonweng ChoJulio Fernandez-BanetSe Kyung LeeSeok Won KimJeong Eon LeeYoon-La ChoiShibing DengJi-Yeon KimJin Seok AhnYing ShaXinmeng Jasmine MuJae-Yong NamYoung-Hyuck ImSoohyeon LeeWoong-Yang ParkSeok Jin NamYeon Hee ParkNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhengyan Kan Ying Ding Jinho Kim Hae Hyun Jung Woosung Chung Samir Lal Soonweng Cho Julio Fernandez-Banet Se Kyung Lee Seok Won Kim Jeong Eon Lee Yoon-La Choi Shibing Deng Ji-Yeon Kim Jin Seok Ahn Ying Sha Xinmeng Jasmine Mu Jae-Yong Nam Young-Hyuck Im Soohyeon Lee Woong-Yang Park Seok Jin Nam Yeon Hee Park Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures
description	While breast cancer incidence in the Asia Pacific region is rising, the molecular basis remains poorly characterized. Here the authors perform genomic screening of 187 Korean breast cancer patients and find differences in molecular subtype distribution, mutation pattern and prevalence, and gene expression signature when compared to TCGA.
format	article
author	Zhengyan Kan Ying Ding Jinho Kim Hae Hyun Jung Woosung Chung Samir Lal Soonweng Cho Julio Fernandez-Banet Se Kyung Lee Seok Won Kim Jeong Eon Lee Yoon-La Choi Shibing Deng Ji-Yeon Kim Jin Seok Ahn Ying Sha Xinmeng Jasmine Mu Jae-Yong Nam Young-Hyuck Im Soohyeon Lee Woong-Yang Park Seok Jin Nam Yeon Hee Park
author_facet	Zhengyan Kan Ying Ding Jinho Kim Hae Hyun Jung Woosung Chung Samir Lal Soonweng Cho Julio Fernandez-Banet Se Kyung Lee Seok Won Kim Jeong Eon Lee Yoon-La Choi Shibing Deng Ji-Yeon Kim Jin Seok Ahn Ying Sha Xinmeng Jasmine Mu Jae-Yong Nam Young-Hyuck Im Soohyeon Lee Woong-Yang Park Seok Jin Nam Yeon Hee Park
author_sort	Zhengyan Kan
title	Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures
title_short	Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures
title_full	Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures
title_fullStr	Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures
title_full_unstemmed	Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures
title_sort	multi-omics profiling of younger asian breast cancers reveals distinctive molecular signatures
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/389b15f6241d433099ba837bc4efcf72
work_keys_str_mv	AT zhengyankan multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT yingding multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT jinhokim multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT haehyunjung multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT woosungchung multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT samirlal multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT soonwengcho multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT juliofernandezbanet multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT sekyunglee multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT seokwonkim multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT jeongeonlee multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT yoonlachoi multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT shibingdeng multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT jiyeonkim multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT jinseokahn multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT yingsha multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT xinmengjasminemu multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT jaeyongnam multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT younghyuckim multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT soohyeonlee multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT woongyangpark multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT seokjinnam multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures AT yeonheepark multiomicsprofilingofyoungerasianbreastcancersrevealsdistinctivemolecularsignatures
_version_	1718380667046199296

Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures

Ejemplares similares