An Experimental Study: Benefits of Digoxin on Hepatotoxicity Induced by Methotrexate Treatment

Purpose. The aim of the study is to examine the possible therapeutic effects of a known cardiac glycoside, digoxin, on a rat model of MTX-induced hepatotoxicity. Methods. The study was conducted on twenty-four male rats. While eighteen rats received a single dose of 20 mg/kg MTX to obtain an injured...

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Bibliographic Details
Main Authors: Banu Taskin, Mümin Alper Erdoğan, Gürkan Yiğittürk, Sibel Alper, Oytun Erbaş
Format: article
Language:EN
Published: Hindawi Limited 2021
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Online Access:https://doaj.org/article/389d3ec6e17b4f0a973c8907a7d6a429
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