Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

Here, Imamuraet al. conduct meta-analysis of genome-wide association studies to identify novel susceptibility loci for type 2 diabetes (T2D) in the Japanese population. By doing so, this study shows that both ethnicity-specific and ethnically-shared genetic loci can contribute to T2D risk.

Guardado en:

Detalles Bibliográficos
Autores principales:	Minako Imamura, Atsushi Takahashi, Toshimasa Yamauchi, Kazuo Hara, Kazuki Yasuda, Niels Grarup, Wei Zhao, Xu Wang, Alicia Huerta-Chagoya, Cheng Hu, Sanghoon Moon, Jirong Long, Soo Heon Kwak, Asif Rasheed, Richa Saxena, Ronald C. W. Ma, Yukinori Okada, Minoru Iwata, Jun Hosoe, Nobuhiro Shojima, Minaka Iwasaki, Hayato Fujita, Ken Suzuki, John Danesh, Torben Jørgensen, Marit E. Jørgensen, Daniel R. Witte, Ivan Brandslund, Cramer Christensen, Torben Hansen, Josep M. Mercader, Jason Flannick, Hortensia Moreno-Macías, Noël P. Burtt, Rong Zhang, Young Jin Kim, Wei Zheng, Jai Rup Singh, Claudia H. T. Tam, Hiroshi Hirose, Hiroshi Maegawa, Chikako Ito, Kohei Kaku, Hirotaka Watada, Yasushi Tanaka, Kazuyuki Tobe, Ryuzo Kawamori, Michiaki Kubo, Yoon Shin Cho, Juliana C. N. Chan, Dharambir Sanghera, Philippe Frossard, Kyong Soo Park, Xiao-Ou Shu, Bong-Jo Kim, Jose C. Florez, Teresa Tusié-Luna, Weiping Jia, E Shyong Tai, Oluf Pedersen, Danish Saleheen, Shiro Maeda, Takashi Kadowaki
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/389e503091f247e28b5236cff3387f83
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:389e503091f247e28b5236cff3387f83
record_format	dspace
spelling	oai:doaj.org-article:389e503091f247e28b5236cff3387f832021-12-02T17:32:52ZGenome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes10.1038/ncomms105312041-1723https://doaj.org/article/389e503091f247e28b5236cff3387f832016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10531https://doaj.org/toc/2041-1723Here, Imamuraet al. conduct meta-analysis of genome-wide association studies to identify novel susceptibility loci for type 2 diabetes (T2D) in the Japanese population. By doing so, this study shows that both ethnicity-specific and ethnically-shared genetic loci can contribute to T2D risk.Minako ImamuraAtsushi TakahashiToshimasa YamauchiKazuo HaraKazuki YasudaNiels GrarupWei ZhaoXu WangAlicia Huerta-ChagoyaCheng HuSanghoon MoonJirong LongSoo Heon KwakAsif RasheedRicha SaxenaRonald C. W. MaYukinori OkadaMinoru IwataJun HosoeNobuhiro ShojimaMinaka IwasakiHayato FujitaKen SuzukiJohn DaneshTorben JørgensenMarit E. JørgensenDaniel R. WitteIvan BrandslundCramer ChristensenTorben HansenJosep M. MercaderJason FlannickHortensia Moreno-MacíasNoël P. BurttRong ZhangYoung Jin KimWei ZhengJai Rup SinghClaudia H. T. TamHiroshi HiroseHiroshi MaegawaChikako ItoKohei KakuHirotaka WatadaYasushi TanakaKazuyuki TobeRyuzo KawamoriMichiaki KuboYoon Shin ChoJuliana C. N. ChanDharambir SangheraPhilippe FrossardKyong Soo ParkXiao-Ou ShuBong-Jo KimJose C. FlorezTeresa Tusié-LunaWeiping JiaE Shyong TaiOluf PedersenDanish SaleheenShiro MaedaTakashi KadowakiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Minako Imamura Atsushi Takahashi Toshimasa Yamauchi Kazuo Hara Kazuki Yasuda Niels Grarup Wei Zhao Xu Wang Alicia Huerta-Chagoya Cheng Hu Sanghoon Moon Jirong Long Soo Heon Kwak Asif Rasheed Richa Saxena Ronald C. W. Ma Yukinori Okada Minoru Iwata Jun Hosoe Nobuhiro Shojima Minaka Iwasaki Hayato Fujita Ken Suzuki John Danesh Torben Jørgensen Marit E. Jørgensen Daniel R. Witte Ivan Brandslund Cramer Christensen Torben Hansen Josep M. Mercader Jason Flannick Hortensia Moreno-Macías Noël P. Burtt Rong Zhang Young Jin Kim Wei Zheng Jai Rup Singh Claudia H. T. Tam Hiroshi Hirose Hiroshi Maegawa Chikako Ito Kohei Kaku Hirotaka Watada Yasushi Tanaka Kazuyuki Tobe Ryuzo Kawamori Michiaki Kubo Yoon Shin Cho Juliana C. N. Chan Dharambir Sanghera Philippe Frossard Kyong Soo Park Xiao-Ou Shu Bong-Jo Kim Jose C. Florez Teresa Tusié-Luna Weiping Jia E Shyong Tai Oluf Pedersen Danish Saleheen Shiro Maeda Takashi Kadowaki Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
description	Here, Imamuraet al. conduct meta-analysis of genome-wide association studies to identify novel susceptibility loci for type 2 diabetes (T2D) in the Japanese population. By doing so, this study shows that both ethnicity-specific and ethnically-shared genetic loci can contribute to T2D risk.
format	article
author	Minako Imamura Atsushi Takahashi Toshimasa Yamauchi Kazuo Hara Kazuki Yasuda Niels Grarup Wei Zhao Xu Wang Alicia Huerta-Chagoya Cheng Hu Sanghoon Moon Jirong Long Soo Heon Kwak Asif Rasheed Richa Saxena Ronald C. W. Ma Yukinori Okada Minoru Iwata Jun Hosoe Nobuhiro Shojima Minaka Iwasaki Hayato Fujita Ken Suzuki John Danesh Torben Jørgensen Marit E. Jørgensen Daniel R. Witte Ivan Brandslund Cramer Christensen Torben Hansen Josep M. Mercader Jason Flannick Hortensia Moreno-Macías Noël P. Burtt Rong Zhang Young Jin Kim Wei Zheng Jai Rup Singh Claudia H. T. Tam Hiroshi Hirose Hiroshi Maegawa Chikako Ito Kohei Kaku Hirotaka Watada Yasushi Tanaka Kazuyuki Tobe Ryuzo Kawamori Michiaki Kubo Yoon Shin Cho Juliana C. N. Chan Dharambir Sanghera Philippe Frossard Kyong Soo Park Xiao-Ou Shu Bong-Jo Kim Jose C. Florez Teresa Tusié-Luna Weiping Jia E Shyong Tai Oluf Pedersen Danish Saleheen Shiro Maeda Takashi Kadowaki
author_facet	Minako Imamura Atsushi Takahashi Toshimasa Yamauchi Kazuo Hara Kazuki Yasuda Niels Grarup Wei Zhao Xu Wang Alicia Huerta-Chagoya Cheng Hu Sanghoon Moon Jirong Long Soo Heon Kwak Asif Rasheed Richa Saxena Ronald C. W. Ma Yukinori Okada Minoru Iwata Jun Hosoe Nobuhiro Shojima Minaka Iwasaki Hayato Fujita Ken Suzuki John Danesh Torben Jørgensen Marit E. Jørgensen Daniel R. Witte Ivan Brandslund Cramer Christensen Torben Hansen Josep M. Mercader Jason Flannick Hortensia Moreno-Macías Noël P. Burtt Rong Zhang Young Jin Kim Wei Zheng Jai Rup Singh Claudia H. T. Tam Hiroshi Hirose Hiroshi Maegawa Chikako Ito Kohei Kaku Hirotaka Watada Yasushi Tanaka Kazuyuki Tobe Ryuzo Kawamori Michiaki Kubo Yoon Shin Cho Juliana C. N. Chan Dharambir Sanghera Philippe Frossard Kyong Soo Park Xiao-Ou Shu Bong-Jo Kim Jose C. Florez Teresa Tusié-Luna Weiping Jia E Shyong Tai Oluf Pedersen Danish Saleheen Shiro Maeda Takashi Kadowaki
author_sort	Minako Imamura
title	Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
title_short	Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
title_full	Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
title_fullStr	Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
title_full_unstemmed	Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
title_sort	genome-wide association studies in the japanese population identify seven novel loci for type 2 diabetes
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/389e503091f247e28b5236cff3387f83
work_keys_str_mv	AT minakoimamura genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT atsushitakahashi genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT toshimasayamauchi genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT kazuohara genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT kazukiyasuda genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT nielsgrarup genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT weizhao genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT xuwang genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT aliciahuertachagoya genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT chenghu genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT sanghoonmoon genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT jironglong genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT sooheonkwak genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT asifrasheed genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT richasaxena genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT ronaldcwma genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT yukinoriokada genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT minoruiwata genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT junhosoe genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT nobuhiroshojima genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT minakaiwasaki genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT hayatofujita genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT kensuzuki genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT johndanesh genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT torbenjørgensen genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT maritejørgensen genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT danielrwitte genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT ivanbrandslund genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT cramerchristensen genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT torbenhansen genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT josepmmercader genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT jasonflannick genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT hortensiamorenomacias genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT noelpburtt genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT rongzhang genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT youngjinkim genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT weizheng genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT jairupsingh genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT claudiahttam genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT hiroshihirose genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT hiroshimaegawa genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT chikakoito genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT koheikaku genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT hirotakawatada genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT yasushitanaka genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT kazuyukitobe genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT ryuzokawamori genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT michiakikubo genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT yoonshincho genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT julianacnchan genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT dharambirsanghera genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT philippefrossard genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT kyongsoopark genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT xiaooushu genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT bongjokim genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT josecflorez genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT teresatusieluna genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT weipingjia genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT eshyongtai genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT olufpedersen genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT danishsaleheen genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT shiromaeda genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes AT takashikadowaki genomewideassociationstudiesinthejapanesepopulationidentifysevennovellocifortype2diabetes
_version_	1718380177928486912

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

Ejemplares similares