Treatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral

Background: this study evaluates the clinical outcomes of a novel approach in treating deep intrabony defects utilizing papilla preservation techniques with a combination of hyaluronic acid (HA) and deproteinized porcine bone mineral. Methods: 23 patients with 27 intrabony defects were treated with...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Darko Božić, Ivan Ćatović, Ana Badovinac, Larisa Musić, Matej Par, Anton Sculean
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	hyaluronic acid periodontal regeneration intrabony defects microsurgery periodontitis surgical flaps Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85
Acceso en línea:	https://doaj.org/article/38a4347623c04460917bde9d58b7dfe4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:38a4347623c04460917bde9d58b7dfe4
record_format	dspace
spelling	oai:doaj.org-article:38a4347623c04460917bde9d58b7dfe42021-11-25T18:13:37ZTreatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral10.3390/ma142267951996-1944https://doaj.org/article/38a4347623c04460917bde9d58b7dfe42021-11-01T00:00:00Zhttps://www.mdpi.com/1996-1944/14/22/6795https://doaj.org/toc/1996-1944Background: this study evaluates the clinical outcomes of a novel approach in treating deep intrabony defects utilizing papilla preservation techniques with a combination of hyaluronic acid (HA) and deproteinized porcine bone mineral. Methods: 23 patients with 27 intrabony defects were treated with a combination of HA and deproteinized porcine bone mineral. Clinical attachment level (CAL), pocket probing depth (PPD), gingival recession (REC) were recorded at baseline and 6 months after the surgery. Results: At 6 months, there was a significant CAL gain of 3.65 ± 1.67 mm (<i>p</i> < 0.001) with a PPD reduction of 4.54 ± 1.65 mm (<i>p</i> < 0.001), which was associated with an increase in gingival recession (0.89 ± 0.59 mm, <i>p</i> < 0.001). The percentage of pocket resolution based on a PPD ≤4 mm was 92.6% and the failure rate based on a PPD of 5 mm was 7.4%. Conclusions: the present findings indicate that applying a combined HA and xenograft approach in deep intrabony defects provides clinically relevant CAL gains and PPD reductions compared to baseline values and is a valid new approach in treating intrabony defects.Darko BožićIvan ĆatovićAna BadovinacLarisa MusićMatej ParAnton SculeanMDPI AGarticlehyaluronic acidperiodontal regenerationintrabony defectsmicrosurgeryperiodontitissurgical flapsTechnologyTElectrical engineering. Electronics. Nuclear engineeringTK1-9971Engineering (General). Civil engineering (General)TA1-2040MicroscopyQH201-278.5Descriptive and experimental mechanicsQC120-168.85ENMaterials, Vol 14, Iss 6795, p 6795 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	hyaluronic acid periodontal regeneration intrabony defects microsurgery periodontitis surgical flaps Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85
spellingShingle	hyaluronic acid periodontal regeneration intrabony defects microsurgery periodontitis surgical flaps Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85 Darko Božić Ivan Ćatović Ana Badovinac Larisa Musić Matej Par Anton Sculean Treatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral
description	Background: this study evaluates the clinical outcomes of a novel approach in treating deep intrabony defects utilizing papilla preservation techniques with a combination of hyaluronic acid (HA) and deproteinized porcine bone mineral. Methods: 23 patients with 27 intrabony defects were treated with a combination of HA and deproteinized porcine bone mineral. Clinical attachment level (CAL), pocket probing depth (PPD), gingival recession (REC) were recorded at baseline and 6 months after the surgery. Results: At 6 months, there was a significant CAL gain of 3.65 ± 1.67 mm (<i>p</i> < 0.001) with a PPD reduction of 4.54 ± 1.65 mm (<i>p</i> < 0.001), which was associated with an increase in gingival recession (0.89 ± 0.59 mm, <i>p</i> < 0.001). The percentage of pocket resolution based on a PPD ≤4 mm was 92.6% and the failure rate based on a PPD of 5 mm was 7.4%. Conclusions: the present findings indicate that applying a combined HA and xenograft approach in deep intrabony defects provides clinically relevant CAL gains and PPD reductions compared to baseline values and is a valid new approach in treating intrabony defects.
format	article
author	Darko Božić Ivan Ćatović Ana Badovinac Larisa Musić Matej Par Anton Sculean
author_facet	Darko Božić Ivan Ćatović Ana Badovinac Larisa Musić Matej Par Anton Sculean
author_sort	Darko Božić
title	Treatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral
title_short	Treatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral
title_full	Treatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral
title_fullStr	Treatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral
title_full_unstemmed	Treatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral
title_sort	treatment of intrabony defects with a combination of hyaluronic acid and deproteinized porcine bone mineral
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/38a4347623c04460917bde9d58b7dfe4
work_keys_str_mv	AT darkobozic treatmentofintrabonydefectswithacombinationofhyaluronicacidanddeproteinizedporcinebonemineral AT ivancatovic treatmentofintrabonydefectswithacombinationofhyaluronicacidanddeproteinizedporcinebonemineral AT anabadovinac treatmentofintrabonydefectswithacombinationofhyaluronicacidanddeproteinizedporcinebonemineral AT larisamusic treatmentofintrabonydefectswithacombinationofhyaluronicacidanddeproteinizedporcinebonemineral AT matejpar treatmentofintrabonydefectswithacombinationofhyaluronicacidanddeproteinizedporcinebonemineral AT antonsculean treatmentofintrabonydefectswithacombinationofhyaluronicacidanddeproteinizedporcinebonemineral
_version_	1718411431202783232

Treatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral

Ejemplares similares