DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration

Sk. Kayum Alam et al. show that DARPP-32 isoforms, mediators of dopamine signaling, promote lung tumor growth through non-canonical NF-κB signaling. This study suggests a possibility of using DARPP-32 isoforms as a prognostic marker for lung cancer.

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Autores principales:	Sk. Kayum Alam, Matteo Astone, Ping Liu, Stephanie R. Hall, Abbygail M. Coyle, Erin N. Dankert, Dane K. Hoffman, Wei Zhang, Rui Kuang, Anja C. Roden, Aaron S. Mansfield, Luke H. Hoeppner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/38a7c18c54fe45189102b95eae61c393
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:38a7c18c54fe45189102b95eae61c3932021-12-02T12:30:50ZDARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration10.1038/s42003-018-0050-62399-3642https://doaj.org/article/38a7c18c54fe45189102b95eae61c3932018-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-018-0050-6https://doaj.org/toc/2399-3642Sk. Kayum Alam et al. show that DARPP-32 isoforms, mediators of dopamine signaling, promote lung tumor growth through non-canonical NF-κB signaling. This study suggests a possibility of using DARPP-32 isoforms as a prognostic marker for lung cancer.Sk. Kayum AlamMatteo AstonePing LiuStephanie R. HallAbbygail M. CoyleErin N. DankertDane K. HoffmanWei ZhangRui KuangAnja C. RodenAaron S. MansfieldLuke H. HoeppnerNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 1, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Sk. Kayum Alam Matteo Astone Ping Liu Stephanie R. Hall Abbygail M. Coyle Erin N. Dankert Dane K. Hoffman Wei Zhang Rui Kuang Anja C. Roden Aaron S. Mansfield Luke H. Hoeppner DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration
description	Sk. Kayum Alam et al. show that DARPP-32 isoforms, mediators of dopamine signaling, promote lung tumor growth through non-canonical NF-κB signaling. This study suggests a possibility of using DARPP-32 isoforms as a prognostic marker for lung cancer.
format	article
author	Sk. Kayum Alam Matteo Astone Ping Liu Stephanie R. Hall Abbygail M. Coyle Erin N. Dankert Dane K. Hoffman Wei Zhang Rui Kuang Anja C. Roden Aaron S. Mansfield Luke H. Hoeppner
author_facet	Sk. Kayum Alam Matteo Astone Ping Liu Stephanie R. Hall Abbygail M. Coyle Erin N. Dankert Dane K. Hoffman Wei Zhang Rui Kuang Anja C. Roden Aaron S. Mansfield Luke H. Hoeppner
author_sort	Sk. Kayum Alam
title	DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration
title_short	DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration
title_full	DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration
title_fullStr	DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration
title_full_unstemmed	DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration
title_sort	darpp-32 and t-darpp promote non-small cell lung cancer growth through regulation of ikkα-dependent cell migration
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/38a7c18c54fe45189102b95eae61c393
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DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration

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