Fabrication of ZnO-Ag bimetallic nanoparticles by laser ablation for anticancer activity

The collidal bimentalic nanoparticles of ZnO-Ag were prepared by laser ablation technqiue. The sysenthized bimetalic nanoparticles were characterized by UV–Vis spectrophotometry, Scanning Electron Microscopy (SEM), Energy Dispersive X-ray spectrometry (EDX), Raman spectroscopy, X-ray Photoelectron S...

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Autores principales: Khaled A. Elsayed, Munther Alomari, Q.A. Drmosh, Muidh Alheshibri, Abbad Al Baroot, T.S. Kayed, Abdullah A. Manda, Amal L. Al-Alotaibi
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Lenguaje:EN
Publicado: Elsevier 2022
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Acceso en línea:https://doaj.org/article/38a95a6755d04900ba8b807c1ab26cfc
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spelling oai:doaj.org-article:38a95a6755d04900ba8b807c1ab26cfc2021-11-20T04:56:12ZFabrication of ZnO-Ag bimetallic nanoparticles by laser ablation for anticancer activity1110-016810.1016/j.aej.2021.06.051https://doaj.org/article/38a95a6755d04900ba8b807c1ab26cfc2022-02-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1110016821004142https://doaj.org/toc/1110-0168The collidal bimentalic nanoparticles of ZnO-Ag were prepared by laser ablation technqiue. The sysenthized bimetalic nanoparticles were characterized by UV–Vis spectrophotometry, Scanning Electron Microscopy (SEM), Energy Dispersive X-ray spectrometry (EDX), Raman spectroscopy, X-ray Photoelectron Spectroscopy (XPS), and Photo-Luminescence (PL). These techniques confirmed the formation of the bimetalic nanocompiste and showed that the size distribution of the synthesized bimetallic nanoparticles varied from 30 to 130 nm. The anticancer activity was validated by measuring the cell cytotocicty by MTT (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide) test applying HCT-116 and HELA cancer cell line. The cell lines’ sensitivity was the highest at 10 µg/mL of ZnO-Ag composite. This indicates that the bimetallic composite ZnO-Ag prepared by laser ablation technique is suitable for cancer treatment.Khaled A. ElsayedMunther AlomariQ.A. DrmoshMuidh AlheshibriAbbad Al BarootT.S. KayedAbdullah A. MandaAmal L. Al-AlotaibiElsevierarticleLaser ablationZnO-Ag bimetalic nanoparticlesCancer cellCytotocictyAnticancer activityEngineering (General). Civil engineering (General)TA1-2040ENAlexandria Engineering Journal, Vol 61, Iss 2, Pp 1449-1457 (2022)
institution DOAJ
collection DOAJ
language EN
topic Laser ablation
ZnO-Ag bimetalic nanoparticles
Cancer cell
Cytotocicty
Anticancer activity
Engineering (General). Civil engineering (General)
TA1-2040
spellingShingle Laser ablation
ZnO-Ag bimetalic nanoparticles
Cancer cell
Cytotocicty
Anticancer activity
Engineering (General). Civil engineering (General)
TA1-2040
Khaled A. Elsayed
Munther Alomari
Q.A. Drmosh
Muidh Alheshibri
Abbad Al Baroot
T.S. Kayed
Abdullah A. Manda
Amal L. Al-Alotaibi
Fabrication of ZnO-Ag bimetallic nanoparticles by laser ablation for anticancer activity
description The collidal bimentalic nanoparticles of ZnO-Ag were prepared by laser ablation technqiue. The sysenthized bimetalic nanoparticles were characterized by UV–Vis spectrophotometry, Scanning Electron Microscopy (SEM), Energy Dispersive X-ray spectrometry (EDX), Raman spectroscopy, X-ray Photoelectron Spectroscopy (XPS), and Photo-Luminescence (PL). These techniques confirmed the formation of the bimetalic nanocompiste and showed that the size distribution of the synthesized bimetallic nanoparticles varied from 30 to 130 nm. The anticancer activity was validated by measuring the cell cytotocicty by MTT (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide) test applying HCT-116 and HELA cancer cell line. The cell lines’ sensitivity was the highest at 10 µg/mL of ZnO-Ag composite. This indicates that the bimetallic composite ZnO-Ag prepared by laser ablation technique is suitable for cancer treatment.
format article
author Khaled A. Elsayed
Munther Alomari
Q.A. Drmosh
Muidh Alheshibri
Abbad Al Baroot
T.S. Kayed
Abdullah A. Manda
Amal L. Al-Alotaibi
author_facet Khaled A. Elsayed
Munther Alomari
Q.A. Drmosh
Muidh Alheshibri
Abbad Al Baroot
T.S. Kayed
Abdullah A. Manda
Amal L. Al-Alotaibi
author_sort Khaled A. Elsayed
title Fabrication of ZnO-Ag bimetallic nanoparticles by laser ablation for anticancer activity
title_short Fabrication of ZnO-Ag bimetallic nanoparticles by laser ablation for anticancer activity
title_full Fabrication of ZnO-Ag bimetallic nanoparticles by laser ablation for anticancer activity
title_fullStr Fabrication of ZnO-Ag bimetallic nanoparticles by laser ablation for anticancer activity
title_full_unstemmed Fabrication of ZnO-Ag bimetallic nanoparticles by laser ablation for anticancer activity
title_sort fabrication of zno-ag bimetallic nanoparticles by laser ablation for anticancer activity
publisher Elsevier
publishDate 2022
url https://doaj.org/article/38a95a6755d04900ba8b807c1ab26cfc
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AT muntheralomari fabricationofznoagbimetallicnanoparticlesbylaserablationforanticanceractivity
AT qadrmosh fabricationofznoagbimetallicnanoparticlesbylaserablationforanticanceractivity
AT muidhalheshibri fabricationofznoagbimetallicnanoparticlesbylaserablationforanticanceractivity
AT abbadalbaroot fabricationofznoagbimetallicnanoparticlesbylaserablationforanticanceractivity
AT tskayed fabricationofznoagbimetallicnanoparticlesbylaserablationforanticanceractivity
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