Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension

The SNARE complex enables the fusion of synaptic vesicles with presynaptic membrane via a zippering process that is modulated by the protein complexin, though the precise mechanism remains unclear. Here, the authors used magnetic tweezers to show how complexin prepares a SNARE complex for fusion und...

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Autores principales:	Min Ju Shon, Haesoo Kim, Tae-Young Yoon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/38af0186841e42e99dfb6e424b4a0c3b
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spelling	oai:doaj.org-article:38af0186841e42e99dfb6e424b4a0c3b2021-12-02T17:32:03ZFocused clamping of a single neuronal SNARE complex by complexin under high mechanical tension10.1038/s41467-018-06122-32041-1723https://doaj.org/article/38af0186841e42e99dfb6e424b4a0c3b2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06122-3https://doaj.org/toc/2041-1723The SNARE complex enables the fusion of synaptic vesicles with presynaptic membrane via a zippering process that is modulated by the protein complexin, though the precise mechanism remains unclear. Here, the authors used magnetic tweezers to show how complexin prepares a SNARE complex for fusion under mechanical tension.Min Ju ShonHaesoo KimTae-Young YoonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Min Ju Shon Haesoo Kim Tae-Young Yoon Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension
description	The SNARE complex enables the fusion of synaptic vesicles with presynaptic membrane via a zippering process that is modulated by the protein complexin, though the precise mechanism remains unclear. Here, the authors used magnetic tweezers to show how complexin prepares a SNARE complex for fusion under mechanical tension.
format	article
author	Min Ju Shon Haesoo Kim Tae-Young Yoon
author_facet	Min Ju Shon Haesoo Kim Tae-Young Yoon
author_sort	Min Ju Shon
title	Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension
title_short	Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension
title_full	Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension
title_fullStr	Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension
title_full_unstemmed	Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension
title_sort	focused clamping of a single neuronal snare complex by complexin under high mechanical tension
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/38af0186841e42e99dfb6e424b4a0c3b
work_keys_str_mv	AT minjushon focusedclampingofasingleneuronalsnarecomplexbycomplexinunderhighmechanicaltension AT haesookim focusedclampingofasingleneuronalsnarecomplexbycomplexinunderhighmechanicaltension AT taeyoungyoon focusedclampingofasingleneuronalsnarecomplexbycomplexinunderhighmechanicaltension
_version_	1718380423065632768

Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension

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