Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension
The SNARE complex enables the fusion of synaptic vesicles with presynaptic membrane via a zippering process that is modulated by the protein complexin, though the precise mechanism remains unclear. Here, the authors used magnetic tweezers to show how complexin prepares a SNARE complex for fusion und...
Enregistré dans:
Auteurs principaux: | Min Ju Shon, Haesoo Kim, Tae-Young Yoon |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/38af0186841e42e99dfb6e424b4a0c3b |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin
par: Nicholas A. Courtney, et autres
Publié: (2019) -
Extreme parsimony in ATP consumption by 20S complexes in the global disassembly of single SNARE complexes
par: Changwon Kim, et autres
Publié: (2021) -
Involvement of complexin 2 in docking, locking and unlocking of different SNARE complexes during sperm capacitation and induced acrosomal exocytosis.
par: Pei-Shiue J Tsai, et autres
Publié: (2012) -
Structural basis for the clamping and Ca2+ activation of SNARE-mediated fusion by synaptotagmin
par: Kirill Grushin, et autres
Publié: (2019) -
Patch clamp-assisted single neuron lipidomics
par: Collin B. Merrill, et autres
Publié: (2017)