The role of backbone hydrogen bonds in the transition state for protein folding of a PDZ domain.
Backbone hydrogen bonds are important for the structure and stability of proteins. However, since conventional site-directed mutagenesis cannot be applied to perturb the backbone, the contribution of these hydrogen bonds in protein folding and stability has been assessed only for a very limited set...
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Autores principales: | Søren W Pedersen, Greta Hultqvist, Kristian Strømgaard, Per Jemth |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/38b07bd6bbf847c7ac2c841f2629ba9a |
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