Current aspects on the management of viral uveitis in immunocompetent individuals

Uwe Pleyer,1 Soon-Phaik Chee1–51Augenklinik, Charité– Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany; 2Ocular Inflammation and Immunology Service, Singapore National Eye Centre, 3Singapore Eye Research Institute, 4Department of Ophthalmol...

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Autores principales:	Pleyer U, Chee SP
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/38bfb49d323c457b9d881e3991dc8adc
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spelling	oai:doaj.org-article:38bfb49d323c457b9d881e3991dc8adc2021-12-02T00:07:55ZCurrent aspects on the management of viral uveitis in immunocompetent individuals1177-5483https://doaj.org/article/38bfb49d323c457b9d881e3991dc8adc2015-06-01T00:00:00Zhttp://www.dovepress.com/current-aspects-on-the-management-of-viral-uveitis-in-immunocompetent--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Uwe Pleyer,1 Soon-Phaik Chee1–51Augenklinik, Charité– Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany; 2Ocular Inflammation and Immunology Service, Singapore National Eye Centre, 3Singapore Eye Research Institute, 4Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, 5Duke-NUS Graduate Medical School Singapore, SingaporeAbstract: Viruses are a fundamental etiology of ocular inflammation, which may affect all structures of the organ. Advances in molecular diagnostics reveal an increasingly broader spectrum of virus-associated intraocular inflammation, including all members of the herpes family, rubella virus, and other more rare causes such as Epstein–Barr and chikungunya virus. In particular, viruses of the herpes family are important causes of anterior and posterior uveitis. Owing to their often fulminant clinical course and persistence in ocular tissues, a clear differential diagnosis between alpha- and beta-type herpes viruses is essential to guide acute and long-term treatment. Here, we review the epidemiology, clinical, and laboratory findings of virus-associated uveitis with emphasis on their therapy and management and include our own experience.Keywords: clinical trials, cytomegalovirus, herpes virus, infection, inflammation, treatment, uveitisPleyer UChee SPDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 1017-1028 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Pleyer U Chee SP Current aspects on the management of viral uveitis in immunocompetent individuals
description	Uwe Pleyer,1 Soon-Phaik Chee1–51Augenklinik, Charité– Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany; 2Ocular Inflammation and Immunology Service, Singapore National Eye Centre, 3Singapore Eye Research Institute, 4Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, 5Duke-NUS Graduate Medical School Singapore, SingaporeAbstract: Viruses are a fundamental etiology of ocular inflammation, which may affect all structures of the organ. Advances in molecular diagnostics reveal an increasingly broader spectrum of virus-associated intraocular inflammation, including all members of the herpes family, rubella virus, and other more rare causes such as Epstein–Barr and chikungunya virus. In particular, viruses of the herpes family are important causes of anterior and posterior uveitis. Owing to their often fulminant clinical course and persistence in ocular tissues, a clear differential diagnosis between alpha- and beta-type herpes viruses is essential to guide acute and long-term treatment. Here, we review the epidemiology, clinical, and laboratory findings of virus-associated uveitis with emphasis on their therapy and management and include our own experience.Keywords: clinical trials, cytomegalovirus, herpes virus, infection, inflammation, treatment, uveitis
format	article
author	Pleyer U Chee SP
author_facet	Pleyer U Chee SP
author_sort	Pleyer U
title	Current aspects on the management of viral uveitis in immunocompetent individuals
title_short	Current aspects on the management of viral uveitis in immunocompetent individuals
title_full	Current aspects on the management of viral uveitis in immunocompetent individuals
title_fullStr	Current aspects on the management of viral uveitis in immunocompetent individuals
title_full_unstemmed	Current aspects on the management of viral uveitis in immunocompetent individuals
title_sort	current aspects on the management of viral uveitis in immunocompetent individuals
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/38bfb49d323c457b9d881e3991dc8adc
work_keys_str_mv	AT pleyeru currentaspectsonthemanagementofviraluveitisinimmunocompetentindividuals AT cheesp currentaspectsonthemanagementofviraluveitisinimmunocompetentindividuals
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Current aspects on the management of viral uveitis in immunocompetent individuals

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