Synthesis runs counter to directional folding of a nascent protein domain
In vivo experiments and optical tweezers force-spectroscopy measurements assessing the co-translational folding of the G-domain from bacterial elongation factor G reveal a sequential folding pathway initiating from the C-terminus. These results suggest that protein folding and synthesis proceed in o...
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Autores principales: | Xiuqi Chen, Nandakumar Rajasekaran, Kaixian Liu, Christian M. Kaiser |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/38ca3b49ed5244118a3c3656fe58a7a2 |
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