Effect of polymorphism in the 5’ promoter region of the TG gene on the milk production traits of Polish Holstein-Friesian cattle
<b>The aim of the study was to determine the relationship between the occurrence of three different point mutations (257C>T, 335A>G and 422 C>T) in the promoter region of the gene encoding thyroglobulin (causing polymorphism) and the milk production traits of cattle. The research was...
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| Autores principales: | , |
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| Formato: | article |
| Lenguaje: | EN PL |
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Polish Society of Animal Production
2020
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| Acceso en línea: | https://doaj.org/article/38d92eba3aba4e69b190f227a03736c1 |
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| Sumario: | <b>The aim of the study was to determine the relationship between the occurrence of three different point mutations (257C>T, 335A>G and 422 C>T) in the promoter region of the gene encoding thyroglobulin (causing polymorphism) and the milk production traits of cattle. The research was conducted on a herd of Polish Holstein-Friesian cows. Genotypes were determined by PCR and its ACRS modification. The frequency of more common alleles for the point mutations was determined: <i>C</i> ‒ 0.830 (257C>T), <i>A</i> ‒ 0.765 (335A>G), and <i>C</i> ‒ 0.635 (422C>T). The statistical analysis showed that all three point mutations in the promoter region of the <i>TG</i> gene significantly (P ≤ 0.05; P ≤ 0.01) affect the analysed milk production traits, i.e. daily milk yield, content of milk fat and protein, and somatic cell count.</b>
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