Effect of polymorphism in the 5’ promoter region of the TG gene on the milk production traits of Polish Holstein-Friesian cattle

<b>The aim of the study was to determine the relationship between the occurrence of three different point mutations (257C>T, 335A>G and 422 C>T) in the promoter region of the gene encoding thyroglobulin (causing polymorphism) and the milk production traits of cattle. The research was...

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Autores principales: Ewa Czerniawska-Piątkowska, Inga Kowalewska-Łuczak
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Lenguaje:EN
PL
Publicado: Polish Society of Animal Production 2020
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SNP
Acceso en línea:https://doaj.org/article/38d92eba3aba4e69b190f227a03736c1
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spelling oai:doaj.org-article:38d92eba3aba4e69b190f227a03736c12021-11-10T10:21:27ZEffect of polymorphism in the 5’ promoter region of the TG gene on the milk production traits of Polish Holstein-Friesian cattle1733-73052719-393410.5604/01.3001.0014.0506https://doaj.org/article/38d92eba3aba4e69b190f227a03736c12020-03-01T00:00:00Zhttp://zootechnical.com/gicid/01.3001.0014.0506http://zootechnical.com/gicid/pdf/01.3001.0014.0506https://doaj.org/toc/1733-7305https://doaj.org/toc/2719-3934<b>The aim of the study was to determine the relationship between the occurrence of three different point mutations (257C>T, 335A>G and 422 C>T) in the promoter region of the gene encoding thyroglobulin (causing polymorphism) and the milk production traits of cattle. The research was conducted on a herd of Polish Holstein-Friesian cows. Genotypes were determined by PCR and its ACRS modification. The frequency of more common alleles for the point mutations was determined: <i>C</i> ‒ 0.830 (257C>T), <i>A</i> ‒ 0.765 (335A>G), and <i>C</i> ‒ 0.635 (422C>T). The statistical analysis showed that all three point mutations in the promoter region of the <i>TG</i> gene significantly (P ≤ 0.05; P ≤ 0.01) affect the analysed milk production traits, i.e. daily milk yield, content of milk fat and protein, and somatic cell count.</b> Ewa Czerniawska-PiątkowskaInga Kowalewska-ŁuczakPolish Society of Animal ProductionarticlethyroglobulincattleSNPmilk production traitsZoologyQL1-991ENPLRoczniki Naukowe Polskiego Towarzystwa Zootechnicznego, Vol 16, Iss 1, Pp 9-16 (2020)
institution DOAJ
collection DOAJ
language EN
PL
topic thyroglobulin
cattle
SNP
milk production traits
Zoology
QL1-991
spellingShingle thyroglobulin
cattle
SNP
milk production traits
Zoology
QL1-991
Ewa Czerniawska-Piątkowska
Inga Kowalewska-Łuczak
Effect of polymorphism in the 5’ promoter region of the TG gene on the milk production traits of Polish Holstein-Friesian cattle
description <b>The aim of the study was to determine the relationship between the occurrence of three different point mutations (257C>T, 335A>G and 422 C>T) in the promoter region of the gene encoding thyroglobulin (causing polymorphism) and the milk production traits of cattle. The research was conducted on a herd of Polish Holstein-Friesian cows. Genotypes were determined by PCR and its ACRS modification. The frequency of more common alleles for the point mutations was determined: <i>C</i> ‒ 0.830 (257C>T), <i>A</i> ‒ 0.765 (335A>G), and <i>C</i> ‒ 0.635 (422C>T). The statistical analysis showed that all three point mutations in the promoter region of the <i>TG</i> gene significantly (P ≤ 0.05; P ≤ 0.01) affect the analysed milk production traits, i.e. daily milk yield, content of milk fat and protein, and somatic cell count.</b>
format article
author Ewa Czerniawska-Piątkowska
Inga Kowalewska-Łuczak
author_facet Ewa Czerniawska-Piątkowska
Inga Kowalewska-Łuczak
author_sort Ewa Czerniawska-Piątkowska
title Effect of polymorphism in the 5’ promoter region of the TG gene on the milk production traits of Polish Holstein-Friesian cattle
title_short Effect of polymorphism in the 5’ promoter region of the TG gene on the milk production traits of Polish Holstein-Friesian cattle
title_full Effect of polymorphism in the 5’ promoter region of the TG gene on the milk production traits of Polish Holstein-Friesian cattle
title_fullStr Effect of polymorphism in the 5’ promoter region of the TG gene on the milk production traits of Polish Holstein-Friesian cattle
title_full_unstemmed Effect of polymorphism in the 5’ promoter region of the TG gene on the milk production traits of Polish Holstein-Friesian cattle
title_sort effect of polymorphism in the 5’ promoter region of the tg gene on the milk production traits of polish holstein-friesian cattle
publisher Polish Society of Animal Production
publishDate 2020
url https://doaj.org/article/38d92eba3aba4e69b190f227a03736c1
work_keys_str_mv AT ewaczerniawskapiatkowska effectofpolymorphisminthe5promoterregionofthetggeneonthemilkproductiontraitsofpolishholsteinfriesiancattle
AT ingakowalewskałuczak effectofpolymorphisminthe5promoterregionofthetggeneonthemilkproductiontraitsofpolishholsteinfriesiancattle
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