Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management

Orna Nitzan,1–3 Mazen Elias,2,4 Bibiana Chazan,1,2 Walid Saliba2,4 1Infectious Disease Unit, Ha’emek Medical Center, Afula, Israel; 2Bruce Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel; 3Infectious Disease Unit, Padeh-Poriya Medi...

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Autores principales:	Nitzan O, Elias M, Chazan B, Saliba W
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/38e45f645a614e3ba3e7de0d744edaa3
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spelling	oai:doaj.org-article:38e45f645a614e3ba3e7de0d744edaa32021-12-02T01:06:23ZUrinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management1178-7007https://doaj.org/article/38e45f645a614e3ba3e7de0d744edaa32015-02-01T00:00:00Zhttp://www.dovepress.com/urinary-tract-infections-in-patients-with-type-2-diabetes-mellitus-rev-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007 Orna Nitzan,1–3 Mazen Elias,2,4 Bibiana Chazan,1,2 Walid Saliba2,4 1Infectious Disease Unit, Ha’emek Medical Center, Afula, Israel; 2Bruce Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel; 3Infectious Disease Unit, Padeh-Poriya Medical Center, 4Department of Internal Medicine C, Ha’emek Medical Center, Afula, Israel Abstract: Urinary tract infections are more common, more severe, and carry worse outcomes in patients with type 2 diabetes mellitus. They are also more often caused by resistant pathogens. Various impairments in the immune system, poor metabolic control, and incomplete bladder emptying due to autonomic neuropathy may all contribute to the enhanced risk of urinary tract infections in these patients. The new anti-diabetic sodium glucose cotransporter 2 inhibitors have not been found to significantly increase the risk of symptomatic urinary tract infections. Symptoms of urinary tract infection are similar to patients without diabetes, though some patients with diabetic neuropathy may have altered clinical signs. Treatment depends on several factors, including: presence of symptoms, severity of systemic symptoms, if infection is localized in the bladder or also involves the kidney, presence of urologic abnormalities, accompanying metabolic alterations, and renal function. There is no indication to treat diabetic patients with asymptomatic bacteriuria. Further studies are needed to improve the treatment of patients with type 2 diabetes and urinary tract infections. Keywords: diabetes mellitus, diagnosis, management, prevalence, urinary tract infectionNitzan OElias MChazan BSaliba W,Dove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2015, Iss default, Pp 129-136 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Nitzan O Elias M Chazan B Saliba W, Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management
description	Orna Nitzan,1–3 Mazen Elias,2,4 Bibiana Chazan,1,2 Walid Saliba2,4 1Infectious Disease Unit, Ha’emek Medical Center, Afula, Israel; 2Bruce Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel; 3Infectious Disease Unit, Padeh-Poriya Medical Center, 4Department of Internal Medicine C, Ha’emek Medical Center, Afula, Israel Abstract: Urinary tract infections are more common, more severe, and carry worse outcomes in patients with type 2 diabetes mellitus. They are also more often caused by resistant pathogens. Various impairments in the immune system, poor metabolic control, and incomplete bladder emptying due to autonomic neuropathy may all contribute to the enhanced risk of urinary tract infections in these patients. The new anti-diabetic sodium glucose cotransporter 2 inhibitors have not been found to significantly increase the risk of symptomatic urinary tract infections. Symptoms of urinary tract infection are similar to patients without diabetes, though some patients with diabetic neuropathy may have altered clinical signs. Treatment depends on several factors, including: presence of symptoms, severity of systemic symptoms, if infection is localized in the bladder or also involves the kidney, presence of urologic abnormalities, accompanying metabolic alterations, and renal function. There is no indication to treat diabetic patients with asymptomatic bacteriuria. Further studies are needed to improve the treatment of patients with type 2 diabetes and urinary tract infections. Keywords: diabetes mellitus, diagnosis, management, prevalence, urinary tract infection
format	article
author	Nitzan O Elias M Chazan B Saliba W,
author_facet	Nitzan O Elias M Chazan B Saliba W,
author_sort	Nitzan O
title	Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management
title_short	Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management
title_full	Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management
title_fullStr	Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management
title_full_unstemmed	Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management
title_sort	urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/38e45f645a614e3ba3e7de0d744edaa3
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Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management

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