Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru

We explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Disease...

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Autores principales:	Brenda M. Galindo-Yllu, Ricardo Rojas-Humpire, Carlos J. Toro-Huamanchumo, Rosmery Gutierrez-Ajalcriña, Anderson N. Soriano
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/38f48b94912040bc959b722887ea16a6
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spelling	oai:doaj.org-article:38f48b94912040bc959b722887ea16a62021-11-29T00:56:59ZSerum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru2090-073210.1155/2021/9933319https://doaj.org/article/38f48b94912040bc959b722887ea16a62021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/9933319https://doaj.org/toc/2090-0732We explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Diseases of Huaycán Hospital. MetS was defined according to Latin American Diabetes Association (ALAD) criteria and IR with surrogate IR markers, triglyceride-to-HDL-C ratio (TG/HDL-C), and triglyceride-to-glucose index (TyG). The association between SUA and MetS and IR was determined using Poisson regression models in a sample of 292 participants with an average age of 46.2 ± 10.6 years. The total prevalence of MetS was 38%, and the individuals with MetS presented mainly alterations in anthropometric parameters (obesity and body fat). Finally, the adjusted regression models showed that women with SUA in the highest tertile increased the prevalence of MetS (PR: 1.71, 95% CI: 1.07–2.74) compared to the lowest tertile of SUA in women, while SUA increased hypertriglyceridemia and IR (TG/HDL-C and TyG) in both sexes. We concluded that SUA is strongly associated with MetS in women, and SUA increases hypertriglyceridemia and IR in both sexes. On the contrary, more research is required regarding the female population.Brenda M. Galindo-YlluRicardo Rojas-HumpireCarlos J. Toro-HuamanchumoRosmery Gutierrez-AjalcriñaAnderson N. SorianoHindawi LimitedarticleNutritional diseases. Deficiency diseasesRC620-627ENJournal of Nutrition and Metabolism, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	Nutritional diseases. Deficiency diseases RC620-627 Brenda M. Galindo-Yllu Ricardo Rojas-Humpire Carlos J. Toro-Huamanchumo Rosmery Gutierrez-Ajalcriña Anderson N. Soriano Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
description	We explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Diseases of Huaycán Hospital. MetS was defined according to Latin American Diabetes Association (ALAD) criteria and IR with surrogate IR markers, triglyceride-to-HDL-C ratio (TG/HDL-C), and triglyceride-to-glucose index (TyG). The association between SUA and MetS and IR was determined using Poisson regression models in a sample of 292 participants with an average age of 46.2 ± 10.6 years. The total prevalence of MetS was 38%, and the individuals with MetS presented mainly alterations in anthropometric parameters (obesity and body fat). Finally, the adjusted regression models showed that women with SUA in the highest tertile increased the prevalence of MetS (PR: 1.71, 95% CI: 1.07–2.74) compared to the lowest tertile of SUA in women, while SUA increased hypertriglyceridemia and IR (TG/HDL-C and TyG) in both sexes. We concluded that SUA is strongly associated with MetS in women, and SUA increases hypertriglyceridemia and IR in both sexes. On the contrary, more research is required regarding the female population.
format	article
author	Brenda M. Galindo-Yllu Ricardo Rojas-Humpire Carlos J. Toro-Huamanchumo Rosmery Gutierrez-Ajalcriña Anderson N. Soriano
author_facet	Brenda M. Galindo-Yllu Ricardo Rojas-Humpire Carlos J. Toro-Huamanchumo Rosmery Gutierrez-Ajalcriña Anderson N. Soriano
author_sort	Brenda M. Galindo-Yllu
title	Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title_short	Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title_full	Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title_fullStr	Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title_full_unstemmed	Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title_sort	serum uric acid is associated with metabolic syndrome and insulin resistance among health personnel from peru
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/38f48b94912040bc959b722887ea16a6
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Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru

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