Contribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review

Lactobacillus iners, first described in 1999, is a prevalent bacterial species of the vaginal microbiome. As L. iners does not easily grow on de Man-Rogosa-Sharpe agar, but can grow anaerobically on blood agar, it has been initially overlooked by traditional culture methods. It was not until the wid...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Nengneng Zheng, Renyong Guo, Jinxi Wang, Wei Zhou, Zongxin Ling
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	bacterial vaginosis dysbiosis Lactobacillus iners sexually transmitted infections vaginal microbiota Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/38fa9e6a9156463fb9d7b28d56cc33fe
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:38fa9e6a9156463fb9d7b28d56cc33fe
record_format	dspace
spelling	oai:doaj.org-article:38fa9e6a9156463fb9d7b28d56cc33fe2021-11-22T06:32:04ZContribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review2235-298810.3389/fcimb.2021.792787https://doaj.org/article/38fa9e6a9156463fb9d7b28d56cc33fe2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcimb.2021.792787/fullhttps://doaj.org/toc/2235-2988Lactobacillus iners, first described in 1999, is a prevalent bacterial species of the vaginal microbiome. As L. iners does not easily grow on de Man-Rogosa-Sharpe agar, but can grow anaerobically on blood agar, it has been initially overlooked by traditional culture methods. It was not until the wide application of molecular biology techniques that the function of L. iners in the vaginal microbiome was carefully explored. L. iners has the smallest genome among known Lactobacilli and it has many probiotic characteristics, but is partly different from other major vaginal Lactobacillus species, such as L. crispatus, in contributing to the maintenance of a healthy vaginal microbiome. It is not only commonly present in the healthy vagina but quite often recovered in high numbers in bacterial vaginosis (BV). Increasing evidence suggests that L. iners is a transitional species that colonizes after the vaginal environment is disturbed and offers overall less protection against vaginal dysbiosis and, subsequently, leads to BV, sexually transmitted infections, and adverse pregnancy outcomes. Accordingly, under certain conditions, L. iners is a genuine vaginal symbiont, but it also seems to be an opportunistic pathogen. Further studies are necessary to identify the exact role of this intriguing species in vaginal health and diseases.Nengneng ZhengRenyong GuoJinxi WangWei ZhouZongxin LingZongxin LingFrontiers Media S.A.articlebacterial vaginosisdysbiosisLactobacillus inerssexually transmitted infectionsvaginal microbiotaMicrobiologyQR1-502ENFrontiers in Cellular and Infection Microbiology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	bacterial vaginosis dysbiosis Lactobacillus iners sexually transmitted infections vaginal microbiota Microbiology QR1-502
spellingShingle	bacterial vaginosis dysbiosis Lactobacillus iners sexually transmitted infections vaginal microbiota Microbiology QR1-502 Nengneng Zheng Renyong Guo Jinxi Wang Wei Zhou Zongxin Ling Zongxin Ling Contribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review
description	Lactobacillus iners, first described in 1999, is a prevalent bacterial species of the vaginal microbiome. As L. iners does not easily grow on de Man-Rogosa-Sharpe agar, but can grow anaerobically on blood agar, it has been initially overlooked by traditional culture methods. It was not until the wide application of molecular biology techniques that the function of L. iners in the vaginal microbiome was carefully explored. L. iners has the smallest genome among known Lactobacilli and it has many probiotic characteristics, but is partly different from other major vaginal Lactobacillus species, such as L. crispatus, in contributing to the maintenance of a healthy vaginal microbiome. It is not only commonly present in the healthy vagina but quite often recovered in high numbers in bacterial vaginosis (BV). Increasing evidence suggests that L. iners is a transitional species that colonizes after the vaginal environment is disturbed and offers overall less protection against vaginal dysbiosis and, subsequently, leads to BV, sexually transmitted infections, and adverse pregnancy outcomes. Accordingly, under certain conditions, L. iners is a genuine vaginal symbiont, but it also seems to be an opportunistic pathogen. Further studies are necessary to identify the exact role of this intriguing species in vaginal health and diseases.
format	article
author	Nengneng Zheng Renyong Guo Jinxi Wang Wei Zhou Zongxin Ling Zongxin Ling
author_facet	Nengneng Zheng Renyong Guo Jinxi Wang Wei Zhou Zongxin Ling Zongxin Ling
author_sort	Nengneng Zheng
title	Contribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review
title_short	Contribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review
title_full	Contribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review
title_fullStr	Contribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review
title_full_unstemmed	Contribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review
title_sort	contribution of lactobacillus iners to vaginal health and diseases: a systematic review
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/38fa9e6a9156463fb9d7b28d56cc33fe
work_keys_str_mv	AT nengnengzheng contributionoflactobacillusinerstovaginalhealthanddiseasesasystematicreview AT renyongguo contributionoflactobacillusinerstovaginalhealthanddiseasesasystematicreview AT jinxiwang contributionoflactobacillusinerstovaginalhealthanddiseasesasystematicreview AT weizhou contributionoflactobacillusinerstovaginalhealthanddiseasesasystematicreview AT zongxinling contributionoflactobacillusinerstovaginalhealthanddiseasesasystematicreview AT zongxinling contributionoflactobacillusinerstovaginalhealthanddiseasesasystematicreview
_version_	1718418094712422400

Contribution of Lactobacillus iners to Vaginal Health and Diseases: A Systematic Review

Ejemplares similares