Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi

Vti1a and Vti1b are SNARE proteins implicated in regulated secretion. Here the authors show that Vti1a and Vti1b control protein sorting at the Golgi, and targeting to the axon, and thereby indirectly control regulated secretion at the synapse.

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Detalles Bibliográficos
Autores principales: Javier Emperador-Melero, Vincent Huson, Jan van Weering, Christian Bollmann, Gabriele Fischer von Mollard, Ruud F. Toonen, Matthijs Verhage
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3904ee17225a4880a65ce6a3485a5952
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Sumario:Vti1a and Vti1b are SNARE proteins implicated in regulated secretion. Here the authors show that Vti1a and Vti1b control protein sorting at the Golgi, and targeting to the axon, and thereby indirectly control regulated secretion at the synapse.