Electrochemical Organic Synthesis of Electron-Rich Biaryl Scaffolds: An Update

Biaryl scaffolds are widely spread in biologically important natural products, in numerous therapeutic agents, but they are also considered a privileged class of ligands and (organo)catalysts; therefore, the development of efficient alternative methodologies to prepare such compounds is always attra...

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Autores principales:	Fabrizio Medici, Simonetta Resta, Alessandra Puglisi, Sergio Rossi, Laura Raimondi, Maurizio Benaglia
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	biaryls electrorganic synthesis aryls coupling electrodes radical chemistry Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/390a16c9854d4080a20f0f7103d53d72
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spelling	oai:doaj.org-article:390a16c9854d4080a20f0f7103d53d722021-11-25T18:28:48ZElectrochemical Organic Synthesis of Electron-Rich Biaryl Scaffolds: An Update10.3390/molecules262269681420-3049https://doaj.org/article/390a16c9854d4080a20f0f7103d53d722021-11-01T00:00:00Zhttps://www.mdpi.com/1420-3049/26/22/6968https://doaj.org/toc/1420-3049Biaryl scaffolds are widely spread in biologically important natural products, in numerous therapeutic agents, but they are also considered a privileged class of ligands and (organo)catalysts; therefore, the development of efficient alternative methodologies to prepare such compounds is always attracting much attention. The present review discusses the organic electrosynthesis of biaryls starting from phenols, anilines, naphthols, and naphthylamines. The most significant examples of the works reported in the last decade are presented and classified according to the single class of molecules: after the introduction, the first three sections relate to the reactions of phenols, naphthols, and anilines, respectively; the other two sections refer to cross-coupling and miscellaneous reactions.Fabrizio MediciSimonetta RestaAlessandra PuglisiSergio RossiLaura RaimondiMaurizio BenagliaMDPI AGarticlebiarylselectrorganic synthesisaryls couplingelectrodesradical chemistryOrganic chemistryQD241-441ENMolecules, Vol 26, Iss 6968, p 6968 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	biaryls electrorganic synthesis aryls coupling electrodes radical chemistry Organic chemistry QD241-441
spellingShingle	biaryls electrorganic synthesis aryls coupling electrodes radical chemistry Organic chemistry QD241-441 Fabrizio Medici Simonetta Resta Alessandra Puglisi Sergio Rossi Laura Raimondi Maurizio Benaglia Electrochemical Organic Synthesis of Electron-Rich Biaryl Scaffolds: An Update
description	Biaryl scaffolds are widely spread in biologically important natural products, in numerous therapeutic agents, but they are also considered a privileged class of ligands and (organo)catalysts; therefore, the development of efficient alternative methodologies to prepare such compounds is always attracting much attention. The present review discusses the organic electrosynthesis of biaryls starting from phenols, anilines, naphthols, and naphthylamines. The most significant examples of the works reported in the last decade are presented and classified according to the single class of molecules: after the introduction, the first three sections relate to the reactions of phenols, naphthols, and anilines, respectively; the other two sections refer to cross-coupling and miscellaneous reactions.
format	article
author	Fabrizio Medici Simonetta Resta Alessandra Puglisi Sergio Rossi Laura Raimondi Maurizio Benaglia
author_facet	Fabrizio Medici Simonetta Resta Alessandra Puglisi Sergio Rossi Laura Raimondi Maurizio Benaglia
author_sort	Fabrizio Medici
title	Electrochemical Organic Synthesis of Electron-Rich Biaryl Scaffolds: An Update
title_short	Electrochemical Organic Synthesis of Electron-Rich Biaryl Scaffolds: An Update
title_full	Electrochemical Organic Synthesis of Electron-Rich Biaryl Scaffolds: An Update
title_fullStr	Electrochemical Organic Synthesis of Electron-Rich Biaryl Scaffolds: An Update
title_full_unstemmed	Electrochemical Organic Synthesis of Electron-Rich Biaryl Scaffolds: An Update
title_sort	electrochemical organic synthesis of electron-rich biaryl scaffolds: an update
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/390a16c9854d4080a20f0f7103d53d72
work_keys_str_mv	AT fabriziomedici electrochemicalorganicsynthesisofelectronrichbiarylscaffoldsanupdate AT simonettaresta electrochemicalorganicsynthesisofelectronrichbiarylscaffoldsanupdate AT alessandrapuglisi electrochemicalorganicsynthesisofelectronrichbiarylscaffoldsanupdate AT sergiorossi electrochemicalorganicsynthesisofelectronrichbiarylscaffoldsanupdate AT lauraraimondi electrochemicalorganicsynthesisofelectronrichbiarylscaffoldsanupdate AT mauriziobenaglia electrochemicalorganicsynthesisofelectronrichbiarylscaffoldsanupdate
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Electrochemical Organic Synthesis of Electron-Rich Biaryl Scaffolds: An Update

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