Synthesis and characterization of genistein magnetic molecularly imprinted polymers and their application in soy sauce products

Abstract In this study, a novel method based on genistein magnetic molecularly imprinted polymers (Gen-MMIPs) was developed utilizing a surface molecular imprinting technique, in which genistein was used as the template molecule and Fe3O4 was used as the carrier. The synthesis of Gen-MMIPs was chara...

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Autores principales:	Ziqi Xie, Yunjing Luo, Zhen Na, Wei Zhang, Yufei Zong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/390db78098fc47c38f3ea54f6286ea1d
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spelling	oai:doaj.org-article:390db78098fc47c38f3ea54f6286ea1d2021-12-05T12:13:39ZSynthesis and characterization of genistein magnetic molecularly imprinted polymers and their application in soy sauce products10.1038/s41598-021-02625-02045-2322https://doaj.org/article/390db78098fc47c38f3ea54f6286ea1d2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02625-0https://doaj.org/toc/2045-2322Abstract In this study, a novel method based on genistein magnetic molecularly imprinted polymers (Gen-MMIPs) was developed utilizing a surface molecular imprinting technique, in which genistein was used as the template molecule and Fe3O4 was used as the carrier. The synthesis of Gen-MMIPs was characterized by using scanning electron microscopy (SEM) and transmission electron microscopy (TEM), which indicated that the diameter of the Gen-MMIPs was approximately 500 nm. Via analysis with a vibrating sample magnetometer (VSM), the saturation magnetization of Gen-MMIPs was determined to be 24.79 emu g−1. Fourier transform infrared (FT-IR) spectroscopy showed that polymer groups were on the surface of the magnetic carrier. Adsorption experiments suggested that the genistein adsorption capability of Gen-MMIPs was 5.81 mg g−1, and adsorption equilibrium was achieved within 20 min. Gen-MMIPs as dispersive solid-phase extraction (dSPE) adsorbents combined with HPLC were used to selectively separate genistein in soy sauce samples, and the recoveries ranged from 85.7 to 88.5% with relative standard deviations (RSDs) less than 5%, which proved that this method can be used for the detection of genistein residues in real samples.Ziqi XieYunjing LuoZhen NaWei ZhangYufei ZongNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ziqi Xie Yunjing Luo Zhen Na Wei Zhang Yufei Zong Synthesis and characterization of genistein magnetic molecularly imprinted polymers and their application in soy sauce products
description	Abstract In this study, a novel method based on genistein magnetic molecularly imprinted polymers (Gen-MMIPs) was developed utilizing a surface molecular imprinting technique, in which genistein was used as the template molecule and Fe3O4 was used as the carrier. The synthesis of Gen-MMIPs was characterized by using scanning electron microscopy (SEM) and transmission electron microscopy (TEM), which indicated that the diameter of the Gen-MMIPs was approximately 500 nm. Via analysis with a vibrating sample magnetometer (VSM), the saturation magnetization of Gen-MMIPs was determined to be 24.79 emu g−1. Fourier transform infrared (FT-IR) spectroscopy showed that polymer groups were on the surface of the magnetic carrier. Adsorption experiments suggested that the genistein adsorption capability of Gen-MMIPs was 5.81 mg g−1, and adsorption equilibrium was achieved within 20 min. Gen-MMIPs as dispersive solid-phase extraction (dSPE) adsorbents combined with HPLC were used to selectively separate genistein in soy sauce samples, and the recoveries ranged from 85.7 to 88.5% with relative standard deviations (RSDs) less than 5%, which proved that this method can be used for the detection of genistein residues in real samples.
format	article
author	Ziqi Xie Yunjing Luo Zhen Na Wei Zhang Yufei Zong
author_facet	Ziqi Xie Yunjing Luo Zhen Na Wei Zhang Yufei Zong
author_sort	Ziqi Xie
title	Synthesis and characterization of genistein magnetic molecularly imprinted polymers and their application in soy sauce products
title_short	Synthesis and characterization of genistein magnetic molecularly imprinted polymers and their application in soy sauce products
title_full	Synthesis and characterization of genistein magnetic molecularly imprinted polymers and their application in soy sauce products
title_fullStr	Synthesis and characterization of genistein magnetic molecularly imprinted polymers and their application in soy sauce products
title_full_unstemmed	Synthesis and characterization of genistein magnetic molecularly imprinted polymers and their application in soy sauce products
title_sort	synthesis and characterization of genistein magnetic molecularly imprinted polymers and their application in soy sauce products
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/390db78098fc47c38f3ea54f6286ea1d
work_keys_str_mv	AT ziqixie synthesisandcharacterizationofgenisteinmagneticmolecularlyimprintedpolymersandtheirapplicationinsoysauceproducts AT yunjingluo synthesisandcharacterizationofgenisteinmagneticmolecularlyimprintedpolymersandtheirapplicationinsoysauceproducts AT zhenna synthesisandcharacterizationofgenisteinmagneticmolecularlyimprintedpolymersandtheirapplicationinsoysauceproducts AT weizhang synthesisandcharacterizationofgenisteinmagneticmolecularlyimprintedpolymersandtheirapplicationinsoysauceproducts AT yufeizong synthesisandcharacterizationofgenisteinmagneticmolecularlyimprintedpolymersandtheirapplicationinsoysauceproducts
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Synthesis and characterization of genistein magnetic molecularly imprinted polymers and their application in soy sauce products

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