Influence of Topiramate on the Synaptic Endings of the Temporal Lobe Neocortex in an Experimental Model of Hyperthermia-Induced Seizures: An Ultrastructural Study

Influence of Topiramate on the Synaptic Endings of the Temporal Lobe Neocortex in an Experimental Model of Hyperthermia-Induced Seizures: An Ultrastructural Study

The objective of this pioneering study was to assess potentially neuroprotective properties of topiramate (TPM), a broad spectrum and newer-generation antiepileptic used against damage to synaptic endings of the temporal lobe neocortex in experimental hyperthermia-induced seizures (HS). TPM (80 mg/k...

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Bibliographic Details
Main Authors: Piotr Sobaniec, Joanna Maria Lotowska, Maria Elzbieta Sobaniec-Lotowska, Milena Zochowska-Sobaniec
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
hyperthermia-induced seizures
experimental febrile seizures
topiramate
ultrastructure of synaptic endings
morphometric analysis
temporal lobe neocortex
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Online Access:https://doaj.org/article/3913a9d2c91c4253ae80718a5e40a68a
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https://doaj.org/article/3913a9d2c91c4253ae80718a5e40a68a

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