A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma

Abstract Ultrasound cyclo plasty (UCP) is a recently developed surgical technique for glaucoma allowing a selective and controlled coagulation of the ciliary body. We herein investigated the long-term efficacy and safety of UCP for the treatment of glaucoma. This prospective study included patients...

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Autores principales:	Giuseppe Giannaccare, Marco Pellegrini, Federico Bernabei, Lara Urbini, Fulvio Bergamini, Lorenzo Ferro Desideri, Alessandro Bagnis, Francesco Biagini, Paola Cassottana, Chiara Del Noce, Adriano Carnevali, Vincenzo Scorcia, Carlo E. Traverso, Aldo Vagge
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/391755b4872b4b0893d2a86e722511f6
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spelling	oai:doaj.org-article:391755b4872b4b0893d2a86e722511f62021-12-02T17:41:26ZA 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma10.1038/s41598-021-92233-92045-2322https://doaj.org/article/391755b4872b4b0893d2a86e722511f62021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92233-9https://doaj.org/toc/2045-2322Abstract Ultrasound cyclo plasty (UCP) is a recently developed surgical technique for glaucoma allowing a selective and controlled coagulation of the ciliary body. We herein investigated the long-term efficacy and safety of UCP for the treatment of glaucoma. This prospective study included patients with primary and secondary glaucoma. All surgeries were performed using the EyeOP1 device (Eye Tech Care, Rillieux-la-Pape, France). Sixty-six patients were included, and 60 completed regularly the 2-year follow-up. Preoperative IOP was 28.5 ± 9.6 mmHg and significantly decreased to 17.0 ± 5.4 at 2 years (p < 0.001). The daily number of both hypotensive eye drops and acetazolamide tablets decreased significantly (respectively, from 2.6 ± 1.1 to 1.7 ± 1.2 and from 0.7 ± 0.8 to 0.2 ± 0.5; both p < 0.001). At 2 years, 68.1% of patients met the definition of qualified success (IOP < 21 mmHg regardless of glaucoma medications) and 10.3% of patients met the definition of complete success (IOP < 21 mmHg without glaucoma medications). No major intra- or postoperative complications occurred; however, 15 eyes required additional glaucoma surgery. These results suggest that UCP is an effective and safe procedure to reduce IOP in glaucoma patients through a 2-year follow-up period.Giuseppe GiannaccareMarco PellegriniFederico BernabeiLara UrbiniFulvio BergaminiLorenzo Ferro DesideriAlessandro BagnisFrancesco BiaginiPaola CassottanaChiara Del NoceAdriano CarnevaliVincenzo ScorciaCarlo E. TraversoAldo VaggeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Giuseppe Giannaccare Marco Pellegrini Federico Bernabei Lara Urbini Fulvio Bergamini Lorenzo Ferro Desideri Alessandro Bagnis Francesco Biagini Paola Cassottana Chiara Del Noce Adriano Carnevali Vincenzo Scorcia Carlo E. Traverso Aldo Vagge A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
description	Abstract Ultrasound cyclo plasty (UCP) is a recently developed surgical technique for glaucoma allowing a selective and controlled coagulation of the ciliary body. We herein investigated the long-term efficacy and safety of UCP for the treatment of glaucoma. This prospective study included patients with primary and secondary glaucoma. All surgeries were performed using the EyeOP1 device (Eye Tech Care, Rillieux-la-Pape, France). Sixty-six patients were included, and 60 completed regularly the 2-year follow-up. Preoperative IOP was 28.5 ± 9.6 mmHg and significantly decreased to 17.0 ± 5.4 at 2 years (p < 0.001). The daily number of both hypotensive eye drops and acetazolamide tablets decreased significantly (respectively, from 2.6 ± 1.1 to 1.7 ± 1.2 and from 0.7 ± 0.8 to 0.2 ± 0.5; both p < 0.001). At 2 years, 68.1% of patients met the definition of qualified success (IOP < 21 mmHg regardless of glaucoma medications) and 10.3% of patients met the definition of complete success (IOP < 21 mmHg without glaucoma medications). No major intra- or postoperative complications occurred; however, 15 eyes required additional glaucoma surgery. These results suggest that UCP is an effective and safe procedure to reduce IOP in glaucoma patients through a 2-year follow-up period.
format	article
author	Giuseppe Giannaccare Marco Pellegrini Federico Bernabei Lara Urbini Fulvio Bergamini Lorenzo Ferro Desideri Alessandro Bagnis Francesco Biagini Paola Cassottana Chiara Del Noce Adriano Carnevali Vincenzo Scorcia Carlo E. Traverso Aldo Vagge
author_facet	Giuseppe Giannaccare Marco Pellegrini Federico Bernabei Lara Urbini Fulvio Bergamini Lorenzo Ferro Desideri Alessandro Bagnis Francesco Biagini Paola Cassottana Chiara Del Noce Adriano Carnevali Vincenzo Scorcia Carlo E. Traverso Aldo Vagge
author_sort	Giuseppe Giannaccare
title	A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title_short	A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title_full	A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title_fullStr	A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title_full_unstemmed	A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
title_sort	2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/391755b4872b4b0893d2a86e722511f6
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A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma

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