Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth

Optogenetics has emerged as a promising means to achieve gene expression control in bioprocess engineering, but current systems cannot respond to fluctuations in growth conditions. Here the authors overcome this limitation and develop an automated optogenetic feedback control system for precise and...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Andreas Milias-Argeitis, Marc Rullan, Stephanie K. Aoki, Peter Buchmann, Mustafa Khammash
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3921466752a54a7c8e863254ac40cc7d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3921466752a54a7c8e863254ac40cc7d
record_format	dspace
spelling	oai:doaj.org-article:3921466752a54a7c8e863254ac40cc7d2021-12-02T17:31:18ZAutomated optogenetic feedback control for precise and robust regulation of gene expression and cell growth10.1038/ncomms125462041-1723https://doaj.org/article/3921466752a54a7c8e863254ac40cc7d2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12546https://doaj.org/toc/2041-1723Optogenetics has emerged as a promising means to achieve gene expression control in bioprocess engineering, but current systems cannot respond to fluctuations in growth conditions. Here the authors overcome this limitation and develop an automated optogenetic feedback control system for precise and robust control of protein production in E. coli.Andreas Milias-ArgeitisMarc RullanStephanie K. AokiPeter BuchmannMustafa KhammashNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andreas Milias-Argeitis Marc Rullan Stephanie K. Aoki Peter Buchmann Mustafa Khammash Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth
description	Optogenetics has emerged as a promising means to achieve gene expression control in bioprocess engineering, but current systems cannot respond to fluctuations in growth conditions. Here the authors overcome this limitation and develop an automated optogenetic feedback control system for precise and robust control of protein production in E. coli.
format	article
author	Andreas Milias-Argeitis Marc Rullan Stephanie K. Aoki Peter Buchmann Mustafa Khammash
author_facet	Andreas Milias-Argeitis Marc Rullan Stephanie K. Aoki Peter Buchmann Mustafa Khammash
author_sort	Andreas Milias-Argeitis
title	Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth
title_short	Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth
title_full	Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth
title_fullStr	Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth
title_full_unstemmed	Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth
title_sort	automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/3921466752a54a7c8e863254ac40cc7d
work_keys_str_mv	AT andreasmiliasargeitis automatedoptogeneticfeedbackcontrolforpreciseandrobustregulationofgeneexpressionandcellgrowth AT marcrullan automatedoptogeneticfeedbackcontrolforpreciseandrobustregulationofgeneexpressionandcellgrowth AT stephaniekaoki automatedoptogeneticfeedbackcontrolforpreciseandrobustregulationofgeneexpressionandcellgrowth AT peterbuchmann automatedoptogeneticfeedbackcontrolforpreciseandrobustregulationofgeneexpressionandcellgrowth AT mustafakhammash automatedoptogeneticfeedbackcontrolforpreciseandrobustregulationofgeneexpressionandcellgrowth
_version_	1718380667229700096

Automated optogenetic feedback control for precise and robust regulation of gene expression and cell growth

Ejemplares similares