The serum squamous cell carcinoma antigen level in inverted sinonasal papilloma and nasal polyps patients

Objective: To clarify whether the serum squamous cell carcinoma antigen (SCCA) levels of patients with inverted papilloma (IP) are different from patients with nasal polyps (NP) and rhinitis. Materials and methods: Serum SCCA levels were measured in 30 patients with IP and 30 patients with NP at one...

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Autores principales:	Chakapan Promsopa, Supakan Suwansri, Paiwon Khuntikij
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2021
Materias:	Serum squamous cell carcinoma antigen Inverted papilloma Nasal polyps Rhinitis Otorhinolaryngology RF1-547 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/392aaf5c6bc24a27a863e4b9a7e9f3c3
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spelling	oai:doaj.org-article:392aaf5c6bc24a27a863e4b9a7e9f3c32021-12-02T14:41:00ZThe serum squamous cell carcinoma antigen level in inverted sinonasal papilloma and nasal polyps patients2095-881110.1016/j.wjorl.2020.02.002https://doaj.org/article/392aaf5c6bc24a27a863e4b9a7e9f3c32021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881120300238https://doaj.org/toc/2095-8811Objective: To clarify whether the serum squamous cell carcinoma antigen (SCCA) levels of patients with inverted papilloma (IP) are different from patients with nasal polyps (NP) and rhinitis. Materials and methods: Serum SCCA levels were measured in 30 patients with IP and 30 patients with NP at one day before surgery and seven days after surgery and measured in 28 patients with rhinitis. Results: Elevated serum SCCA levels (>1.5 ng/ml) were found in 80.0% of patients in the IP group, 6.7% of patients in the NP group and 14.3% of patients in the rhinitis group, which was a significant difference. The medians of serum SCCA levels in the IP, NP and rhinitis groups were 3.9, 0.8 and 1.1 ng/ml, respectively, which was a significant difference. The SCCA level in IP group was not significantly correlated according to Krouse Staging. There was a significant difference in serum SCCA levels between the pre- and postoperative stages in the IP group, at 3.9 and 0.8 ng/ml, respectively, while in the NP group the levels were 0.8 and 1.0 ng/ml, not significantly different. With regard to the IP diagnosis in the IP and NP group based on the SCCA level (>1.5 ng/ml), sensitivity and specificity was 80.0% and 93.3%, respectively. Conclusions: The serum SCCA level in patients with IP was elevated and then it decreased after surgery. This was different from NP and rhinitis patients who mostly had normal levels, which did not change.Chakapan PromsopaSupakan SuwansriPaiwon KhuntikijKeAi Communications Co., Ltd.articleSerum squamous cell carcinoma antigenInverted papillomaNasal polypsRhinitisOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 7, Iss 1, Pp 23-27 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Serum squamous cell carcinoma antigen Inverted papilloma Nasal polyps Rhinitis Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Serum squamous cell carcinoma antigen Inverted papilloma Nasal polyps Rhinitis Otorhinolaryngology RF1-547 Surgery RD1-811 Chakapan Promsopa Supakan Suwansri Paiwon Khuntikij The serum squamous cell carcinoma antigen level in inverted sinonasal papilloma and nasal polyps patients
description	Objective: To clarify whether the serum squamous cell carcinoma antigen (SCCA) levels of patients with inverted papilloma (IP) are different from patients with nasal polyps (NP) and rhinitis. Materials and methods: Serum SCCA levels were measured in 30 patients with IP and 30 patients with NP at one day before surgery and seven days after surgery and measured in 28 patients with rhinitis. Results: Elevated serum SCCA levels (>1.5 ng/ml) were found in 80.0% of patients in the IP group, 6.7% of patients in the NP group and 14.3% of patients in the rhinitis group, which was a significant difference. The medians of serum SCCA levels in the IP, NP and rhinitis groups were 3.9, 0.8 and 1.1 ng/ml, respectively, which was a significant difference. The SCCA level in IP group was not significantly correlated according to Krouse Staging. There was a significant difference in serum SCCA levels between the pre- and postoperative stages in the IP group, at 3.9 and 0.8 ng/ml, respectively, while in the NP group the levels were 0.8 and 1.0 ng/ml, not significantly different. With regard to the IP diagnosis in the IP and NP group based on the SCCA level (>1.5 ng/ml), sensitivity and specificity was 80.0% and 93.3%, respectively. Conclusions: The serum SCCA level in patients with IP was elevated and then it decreased after surgery. This was different from NP and rhinitis patients who mostly had normal levels, which did not change.
format	article
author	Chakapan Promsopa Supakan Suwansri Paiwon Khuntikij
author_facet	Chakapan Promsopa Supakan Suwansri Paiwon Khuntikij
author_sort	Chakapan Promsopa
title	The serum squamous cell carcinoma antigen level in inverted sinonasal papilloma and nasal polyps patients
title_short	The serum squamous cell carcinoma antigen level in inverted sinonasal papilloma and nasal polyps patients
title_full	The serum squamous cell carcinoma antigen level in inverted sinonasal papilloma and nasal polyps patients
title_fullStr	The serum squamous cell carcinoma antigen level in inverted sinonasal papilloma and nasal polyps patients
title_full_unstemmed	The serum squamous cell carcinoma antigen level in inverted sinonasal papilloma and nasal polyps patients
title_sort	serum squamous cell carcinoma antigen level in inverted sinonasal papilloma and nasal polyps patients
publisher	KeAi Communications Co., Ltd.
publishDate	2021
url	https://doaj.org/article/392aaf5c6bc24a27a863e4b9a7e9f3c3
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The serum squamous cell carcinoma antigen level in inverted sinonasal papilloma and nasal polyps patients

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