A demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in Brazil

Abstract Little is known about soft tissue sarcomas (STS) in Brazil, once the federal statistics regarding estimates on incidence and mortality of the most common cancers that affect the Brazilian population currently do not include STS. This study aims to perform a broad evaluation and description...

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Autores principales:	Luiza Ohasi de Figueiredo, Augusto Afonso Guerra Júnior, Francisco de Assis Acurcio, Alessandra Maciel Almeida, Mariângela Leal Cherchiglia, Alberto Julius Alves Wainstein, Luiz Claudio Santos Thuler, Angélica Nogueira-Rodrigues
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/39326a7c01f14284900bd77f2d3721e7
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spelling	oai:doaj.org-article:39326a7c01f14284900bd77f2d3721e72021-11-21T12:17:13ZA demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in Brazil10.1038/s41598-021-02032-52045-2322https://doaj.org/article/39326a7c01f14284900bd77f2d3721e72021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02032-5https://doaj.org/toc/2045-2322Abstract Little is known about soft tissue sarcomas (STS) in Brazil, once the federal statistics regarding estimates on incidence and mortality of the most common cancers that affect the Brazilian population currently do not include STS. This study aims to perform a broad evaluation and description of the epidemiological profile, access to treatment and main clinical outcomes of the Brazilian STS patient. A population-based cohort study of 66,825 patients who underwent procedures related to STS treatment registered in the Brazilian public health system (Sistema Único de Saúde, SUS) databases. Median age was 57 years, 30% of them older than 65 years and 50.7% of the cohort was female. The majority, 50,383 patients (75.4%), was diagnosed between 2008 and 2015. Most prevalent anatomic sites were upper and lower limbs (12.6%) and the registry of sarcomas without a specific location comprehended 29.7% of the cohort. The majority of patients resided in the Northeast (40.2% of the patients). Surgery was the first treatment modality in 77.7% of the cases. For survival analysis, only patients with stage and histological grade information were included. The 1-, 5- and 10-year survival rate of the patients was, respectively, 75.4% (95% CI = 74.1–76.7%), 43.4% (95% CI = 41.5–45.5%) and 18.6% (95% CI = 14.8–23.3%).Luiza Ohasi de FigueiredoAugusto Afonso Guerra JúniorFrancisco de Assis AcurcioAlessandra Maciel AlmeidaMariângela Leal CherchigliaAlberto Julius Alves WainsteinLuiz Claudio Santos ThulerAngélica Nogueira-RodriguesNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Luiza Ohasi de Figueiredo Augusto Afonso Guerra Júnior Francisco de Assis Acurcio Alessandra Maciel Almeida Mariângela Leal Cherchiglia Alberto Julius Alves Wainstein Luiz Claudio Santos Thuler Angélica Nogueira-Rodrigues A demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in Brazil
description	Abstract Little is known about soft tissue sarcomas (STS) in Brazil, once the federal statistics regarding estimates on incidence and mortality of the most common cancers that affect the Brazilian population currently do not include STS. This study aims to perform a broad evaluation and description of the epidemiological profile, access to treatment and main clinical outcomes of the Brazilian STS patient. A population-based cohort study of 66,825 patients who underwent procedures related to STS treatment registered in the Brazilian public health system (Sistema Único de Saúde, SUS) databases. Median age was 57 years, 30% of them older than 65 years and 50.7% of the cohort was female. The majority, 50,383 patients (75.4%), was diagnosed between 2008 and 2015. Most prevalent anatomic sites were upper and lower limbs (12.6%) and the registry of sarcomas without a specific location comprehended 29.7% of the cohort. The majority of patients resided in the Northeast (40.2% of the patients). Surgery was the first treatment modality in 77.7% of the cases. For survival analysis, only patients with stage and histological grade information were included. The 1-, 5- and 10-year survival rate of the patients was, respectively, 75.4% (95% CI = 74.1–76.7%), 43.4% (95% CI = 41.5–45.5%) and 18.6% (95% CI = 14.8–23.3%).
format	article
author	Luiza Ohasi de Figueiredo Augusto Afonso Guerra Júnior Francisco de Assis Acurcio Alessandra Maciel Almeida Mariângela Leal Cherchiglia Alberto Julius Alves Wainstein Luiz Claudio Santos Thuler Angélica Nogueira-Rodrigues
author_facet	Luiza Ohasi de Figueiredo Augusto Afonso Guerra Júnior Francisco de Assis Acurcio Alessandra Maciel Almeida Mariângela Leal Cherchiglia Alberto Julius Alves Wainstein Luiz Claudio Santos Thuler Angélica Nogueira-Rodrigues
author_sort	Luiza Ohasi de Figueiredo
title	A demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in Brazil
title_short	A demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in Brazil
title_full	A demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in Brazil
title_fullStr	A demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in Brazil
title_full_unstemmed	A demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in Brazil
title_sort	demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in brazil
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/39326a7c01f14284900bd77f2d3721e7
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A demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in Brazil

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