Initial Screening of Poly(ethylene glycol) Amino Ligands for Affinity Purification of Plasmid DNA in Aqueous Two-Phase Systems

Gene therapy and DNA vaccination are among the most expected biotechnological and medical advances for the coming years. However, the lack of cost-effective large-scale production and purification of pharmaceutical-grade plasmid DNA (pDNA) still hampers their wide application. Downstream processing,...

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Bibliographic Details
Main Authors: Nuno R. da Silva, Paula Jorge, José A. Martins, José A. Teixeira, João C. Marcos
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/3933f99fe1864318b7a9707462897032
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