NMDAR-mediated modulation of gap junction circuit regulates olfactory learning in C. elegans
Neural plasticity underlies learning and is regulated by modulation of gap junctions. Here, the authors show that NMDAR- and CaMKII-mediated cell autonomous downregulation of gap junction molecules in a circuit of interneurons facilitates olfactory learning affecting behavior in C. elegans.
Guardado en:
Autores principales: | Myung-Kyu Choi, He Liu, Taihong Wu, Wenxing Yang, Yun Zhang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/39398b289a3b4e4591f7870378ecd1af |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Gap junction-mediated regulation of endothelial cellular stiffness
por: Takayuki Okamoto, et al.
Publicado: (2017) -
Opponent vesicular transporters regulate the strength of glutamatergic neurotransmission in a C. elegans sensory circuit
por: Jung-Hwan Choi, et al.
Publicado: (2021) -
An electrostatic mechanism for Ca2+-mediated regulation of gap junction channels
por: Brad C. Bennett, et al.
Publicado: (2016) -
Bounded rationality in C. elegans is explained by circuit-specific normalization in chemosensory pathways
por: Dror Cohen, et al.
Publicado: (2019) -
Synaptotagmin-7-mediated activation of spontaneous NMDAR currents is disrupted in bipolar disorder susceptibility variants.
por: Qiu-Wen Wang, et al.
Publicado: (2021)