A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers

Peripheral nerves have a complex physiology and it is therefore difficult to measure axonal activity in vitro. Here the authors make a nerve-on-a-chip platform to align peripheral nerves and permit measurement of conduction amplitude and velocity along several axons in a single experiment.

Guardado en:

Detalles Bibliográficos
Autores principales:	Sandra Gribi, Sophie du Bois de Dunilac, Diego Ghezzi, Stéphanie P. Lacour
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3952aa09f5c9498a92683bb0bce61588
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3952aa09f5c9498a92683bb0bce61588
record_format	dspace
spelling	oai:doaj.org-article:3952aa09f5c9498a92683bb0bce615882021-12-02T14:39:47ZA microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers10.1038/s41467-018-06895-72041-1723https://doaj.org/article/3952aa09f5c9498a92683bb0bce615882018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06895-7https://doaj.org/toc/2041-1723Peripheral nerves have a complex physiology and it is therefore difficult to measure axonal activity in vitro. Here the authors make a nerve-on-a-chip platform to align peripheral nerves and permit measurement of conduction amplitude and velocity along several axons in a single experiment.Sandra GribiSophie du Bois de DunilacDiego GhezziStéphanie P. LacourNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sandra Gribi Sophie du Bois de Dunilac Diego Ghezzi Stéphanie P. Lacour A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers
description	Peripheral nerves have a complex physiology and it is therefore difficult to measure axonal activity in vitro. Here the authors make a nerve-on-a-chip platform to align peripheral nerves and permit measurement of conduction amplitude and velocity along several axons in a single experiment.
format	article
author	Sandra Gribi Sophie du Bois de Dunilac Diego Ghezzi Stéphanie P. Lacour
author_facet	Sandra Gribi Sophie du Bois de Dunilac Diego Ghezzi Stéphanie P. Lacour
author_sort	Sandra Gribi
title	A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers
title_short	A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers
title_full	A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers
title_fullStr	A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers
title_full_unstemmed	A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers
title_sort	microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3952aa09f5c9498a92683bb0bce61588
work_keys_str_mv	AT sandragribi amicrofabricatednerveonachipplatformforrapidassessmentofneuralconductioninexplantedperipheralnervefibers AT sophieduboisdedunilac amicrofabricatednerveonachipplatformforrapidassessmentofneuralconductioninexplantedperipheralnervefibers AT diegoghezzi amicrofabricatednerveonachipplatformforrapidassessmentofneuralconductioninexplantedperipheralnervefibers AT stephanieplacour amicrofabricatednerveonachipplatformforrapidassessmentofneuralconductioninexplantedperipheralnervefibers AT sandragribi microfabricatednerveonachipplatformforrapidassessmentofneuralconductioninexplantedperipheralnervefibers AT sophieduboisdedunilac microfabricatednerveonachipplatformforrapidassessmentofneuralconductioninexplantedperipheralnervefibers AT diegoghezzi microfabricatednerveonachipplatformforrapidassessmentofneuralconductioninexplantedperipheralnervefibers AT stephanieplacour microfabricatednerveonachipplatformforrapidassessmentofneuralconductioninexplantedperipheralnervefibers
_version_	1718390467261890560

A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers

Ejemplares similares