The m6A “reader” YTHDF1 promotes osteogenesis of bone marrow mesenchymal stem cells through translational control of ZNF839

The m6A “reader” YTHDF1 promotes osteogenesis of bone marrow mesenchymal stem cells through translational control of ZNF839

Abstract N6-methyladenosine (m6A) is required for differentiation of human bone marrow mesenchymal stem cells (hBMSCs). However, its intrinsic mechanisms are largely unknown. To identify the possible role of m6A binding protein YTHDF1 in hBMSCs osteogenesis in vivo, we constructed Ythdf1 KO mice and...

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Autores principales: Tao Liu, Xinfeng Zheng, Chenglong Wang, Chuandong Wang, Shengdan Jiang, Bo Li, Pengbo Chen, Wenning Xu, Huoliang Zheng, Runze Yang, Xingxu Huang, Xiaoling Zhang, Leisheng Jiang
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
Materias:
Cytology
QH573-671
Acceso en línea:https://doaj.org/article/3953421029344d2785051f2392b628fb
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