Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing

The TOR and insulin/IGF signalling (IIS) network are central responses to wound healing. Here the authors develop a technique of live imaging of laser-induced epidermal wounds to flies and show that TOR and IIS are independently required for wound healing, which may have implications for diabetic wo...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Parisa Kakanj, Bernard Moussian, Sebastian Grönke, Victor Bustos, Sabine A. Eming, Linda Partridge, Maria Leptin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/395bcb179a9941d8a7198e487d5e713d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:The TOR and insulin/IGF signalling (IIS) network are central responses to wound healing. Here the authors develop a technique of live imaging of laser-induced epidermal wounds to flies and show that TOR and IIS are independently required for wound healing, which may have implications for diabetic wound healing and its treatment.