Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing

The TOR and insulin/IGF signalling (IIS) network are central responses to wound healing. Here the authors develop a technique of live imaging of laser-induced epidermal wounds to flies and show that TOR and IIS are independently required for wound healing, which may have implications for diabetic wo...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Parisa Kakanj, Bernard Moussian, Sebastian Grönke, Victor Bustos, Sabine A. Eming, Linda Partridge, Maria Leptin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/395bcb179a9941d8a7198e487d5e713d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:395bcb179a9941d8a7198e487d5e713d
record_format dspace
spelling oai:doaj.org-article:395bcb179a9941d8a7198e487d5e713d2021-12-02T15:33:49ZInsulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing10.1038/ncomms129722041-1723https://doaj.org/article/395bcb179a9941d8a7198e487d5e713d2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12972https://doaj.org/toc/2041-1723The TOR and insulin/IGF signalling (IIS) network are central responses to wound healing. Here the authors develop a technique of live imaging of laser-induced epidermal wounds to flies and show that TOR and IIS are independently required for wound healing, which may have implications for diabetic wound healing and its treatment.Parisa KakanjBernard MoussianSebastian GrönkeVictor BustosSabine A. EmingLinda PartridgeMaria LeptinNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Parisa Kakanj
Bernard Moussian
Sebastian Grönke
Victor Bustos
Sabine A. Eming
Linda Partridge
Maria Leptin
Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing
description The TOR and insulin/IGF signalling (IIS) network are central responses to wound healing. Here the authors develop a technique of live imaging of laser-induced epidermal wounds to flies and show that TOR and IIS are independently required for wound healing, which may have implications for diabetic wound healing and its treatment.
format article
author Parisa Kakanj
Bernard Moussian
Sebastian Grönke
Victor Bustos
Sabine A. Eming
Linda Partridge
Maria Leptin
author_facet Parisa Kakanj
Bernard Moussian
Sebastian Grönke
Victor Bustos
Sabine A. Eming
Linda Partridge
Maria Leptin
author_sort Parisa Kakanj
title Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing
title_short Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing
title_full Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing
title_fullStr Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing
title_full_unstemmed Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing
title_sort insulin and tor signal in parallel through foxo and s6k to promote epithelial wound healing
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/395bcb179a9941d8a7198e487d5e713d
work_keys_str_mv AT parisakakanj insulinandtorsignalinparallelthroughfoxoands6ktopromoteepithelialwoundhealing
AT bernardmoussian insulinandtorsignalinparallelthroughfoxoands6ktopromoteepithelialwoundhealing
AT sebastiangronke insulinandtorsignalinparallelthroughfoxoands6ktopromoteepithelialwoundhealing
AT victorbustos insulinandtorsignalinparallelthroughfoxoands6ktopromoteepithelialwoundhealing
AT sabineaeming insulinandtorsignalinparallelthroughfoxoands6ktopromoteepithelialwoundhealing
AT lindapartridge insulinandtorsignalinparallelthroughfoxoands6ktopromoteepithelialwoundhealing
AT marialeptin insulinandtorsignalinparallelthroughfoxoands6ktopromoteepithelialwoundhealing
_version_ 1718387016388837376