Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing
The TOR and insulin/IGF signalling (IIS) network are central responses to wound healing. Here the authors develop a technique of live imaging of laser-induced epidermal wounds to flies and show that TOR and IIS are independently required for wound healing, which may have implications for diabetic wo...
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Nature Portfolio
2016
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oai:doaj.org-article:395bcb179a9941d8a7198e487d5e713d2021-12-02T15:33:49ZInsulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing10.1038/ncomms129722041-1723https://doaj.org/article/395bcb179a9941d8a7198e487d5e713d2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12972https://doaj.org/toc/2041-1723The TOR and insulin/IGF signalling (IIS) network are central responses to wound healing. Here the authors develop a technique of live imaging of laser-induced epidermal wounds to flies and show that TOR and IIS are independently required for wound healing, which may have implications for diabetic wound healing and its treatment.Parisa KakanjBernard MoussianSebastian GrönkeVictor BustosSabine A. EmingLinda PartridgeMaria LeptinNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016) |
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Science Q Parisa Kakanj Bernard Moussian Sebastian Grönke Victor Bustos Sabine A. Eming Linda Partridge Maria Leptin Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing |
description |
The TOR and insulin/IGF signalling (IIS) network are central responses to wound healing. Here the authors develop a technique of live imaging of laser-induced epidermal wounds to flies and show that TOR and IIS are independently required for wound healing, which may have implications for diabetic wound healing and its treatment. |
format |
article |
author |
Parisa Kakanj Bernard Moussian Sebastian Grönke Victor Bustos Sabine A. Eming Linda Partridge Maria Leptin |
author_facet |
Parisa Kakanj Bernard Moussian Sebastian Grönke Victor Bustos Sabine A. Eming Linda Partridge Maria Leptin |
author_sort |
Parisa Kakanj |
title |
Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing |
title_short |
Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing |
title_full |
Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing |
title_fullStr |
Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing |
title_full_unstemmed |
Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing |
title_sort |
insulin and tor signal in parallel through foxo and s6k to promote epithelial wound healing |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/395bcb179a9941d8a7198e487d5e713d |
work_keys_str_mv |
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