RNA editing generates cellular subsets with diverse sequence within populations

RNA editing rate detected from bulk RNA-seq data can vary widely. Here, by constructing a hierarchical Bayesian model, the authors report substantial variance in editing signatures detected by RNA-seq data from both single cells and a cognate bulk sample.

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Autores principales: Dewi Harjanto, Theodore Papamarkou, Chris J. Oates, Violeta Rayon-Estrada, F. Nina Papavasiliou, Anastasia Papavasiliou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/39669e9caefe42a893d07c69afbb336f
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spelling oai:doaj.org-article:39669e9caefe42a893d07c69afbb336f2021-12-02T17:33:09ZRNA editing generates cellular subsets with diverse sequence within populations10.1038/ncomms121452041-1723https://doaj.org/article/39669e9caefe42a893d07c69afbb336f2016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12145https://doaj.org/toc/2041-1723RNA editing rate detected from bulk RNA-seq data can vary widely. Here, by constructing a hierarchical Bayesian model, the authors report substantial variance in editing signatures detected by RNA-seq data from both single cells and a cognate bulk sample.Dewi HarjantoTheodore PapamarkouChris J. OatesVioleta Rayon-EstradaF. Nina PapavasiliouAnastasia PapavasiliouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dewi Harjanto
Theodore Papamarkou
Chris J. Oates
Violeta Rayon-Estrada
F. Nina Papavasiliou
Anastasia Papavasiliou
RNA editing generates cellular subsets with diverse sequence within populations
description RNA editing rate detected from bulk RNA-seq data can vary widely. Here, by constructing a hierarchical Bayesian model, the authors report substantial variance in editing signatures detected by RNA-seq data from both single cells and a cognate bulk sample.
format article
author Dewi Harjanto
Theodore Papamarkou
Chris J. Oates
Violeta Rayon-Estrada
F. Nina Papavasiliou
Anastasia Papavasiliou
author_facet Dewi Harjanto
Theodore Papamarkou
Chris J. Oates
Violeta Rayon-Estrada
F. Nina Papavasiliou
Anastasia Papavasiliou
author_sort Dewi Harjanto
title RNA editing generates cellular subsets with diverse sequence within populations
title_short RNA editing generates cellular subsets with diverse sequence within populations
title_full RNA editing generates cellular subsets with diverse sequence within populations
title_fullStr RNA editing generates cellular subsets with diverse sequence within populations
title_full_unstemmed RNA editing generates cellular subsets with diverse sequence within populations
title_sort rna editing generates cellular subsets with diverse sequence within populations
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/39669e9caefe42a893d07c69afbb336f
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AT chrisjoates rnaeditinggeneratescellularsubsetswithdiversesequencewithinpopulations
AT violetarayonestrada rnaeditinggeneratescellularsubsetswithdiversesequencewithinpopulations
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