RNA editing generates cellular subsets with diverse sequence within populations
RNA editing rate detected from bulk RNA-seq data can vary widely. Here, by constructing a hierarchical Bayesian model, the authors report substantial variance in editing signatures detected by RNA-seq data from both single cells and a cognate bulk sample.
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Nature Portfolio
2016
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oai:doaj.org-article:39669e9caefe42a893d07c69afbb336f2021-12-02T17:33:09ZRNA editing generates cellular subsets with diverse sequence within populations10.1038/ncomms121452041-1723https://doaj.org/article/39669e9caefe42a893d07c69afbb336f2016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12145https://doaj.org/toc/2041-1723RNA editing rate detected from bulk RNA-seq data can vary widely. Here, by constructing a hierarchical Bayesian model, the authors report substantial variance in editing signatures detected by RNA-seq data from both single cells and a cognate bulk sample.Dewi HarjantoTheodore PapamarkouChris J. OatesVioleta Rayon-EstradaF. Nina PapavasiliouAnastasia PapavasiliouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
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Science Q Dewi Harjanto Theodore Papamarkou Chris J. Oates Violeta Rayon-Estrada F. Nina Papavasiliou Anastasia Papavasiliou RNA editing generates cellular subsets with diverse sequence within populations |
description |
RNA editing rate detected from bulk RNA-seq data can vary widely. Here, by constructing a hierarchical Bayesian model, the authors report substantial variance in editing signatures detected by RNA-seq data from both single cells and a cognate bulk sample. |
format |
article |
author |
Dewi Harjanto Theodore Papamarkou Chris J. Oates Violeta Rayon-Estrada F. Nina Papavasiliou Anastasia Papavasiliou |
author_facet |
Dewi Harjanto Theodore Papamarkou Chris J. Oates Violeta Rayon-Estrada F. Nina Papavasiliou Anastasia Papavasiliou |
author_sort |
Dewi Harjanto |
title |
RNA editing generates cellular subsets with diverse sequence within populations |
title_short |
RNA editing generates cellular subsets with diverse sequence within populations |
title_full |
RNA editing generates cellular subsets with diverse sequence within populations |
title_fullStr |
RNA editing generates cellular subsets with diverse sequence within populations |
title_full_unstemmed |
RNA editing generates cellular subsets with diverse sequence within populations |
title_sort |
rna editing generates cellular subsets with diverse sequence within populations |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/39669e9caefe42a893d07c69afbb336f |
work_keys_str_mv |
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1718380056433131520 |