RNA editing generates cellular subsets with diverse sequence within populations

RNA editing rate detected from bulk RNA-seq data can vary widely. Here, by constructing a hierarchical Bayesian model, the authors report substantial variance in editing signatures detected by RNA-seq data from both single cells and a cognate bulk sample.

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Autores principales:	Dewi Harjanto, Theodore Papamarkou, Chris J. Oates, Violeta Rayon-Estrada, F. Nina Papavasiliou, Anastasia Papavasiliou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/39669e9caefe42a893d07c69afbb336f
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id	oai:doaj.org-article:39669e9caefe42a893d07c69afbb336f
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spelling	oai:doaj.org-article:39669e9caefe42a893d07c69afbb336f2021-12-02T17:33:09ZRNA editing generates cellular subsets with diverse sequence within populations10.1038/ncomms121452041-1723https://doaj.org/article/39669e9caefe42a893d07c69afbb336f2016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12145https://doaj.org/toc/2041-1723RNA editing rate detected from bulk RNA-seq data can vary widely. Here, by constructing a hierarchical Bayesian model, the authors report substantial variance in editing signatures detected by RNA-seq data from both single cells and a cognate bulk sample.Dewi HarjantoTheodore PapamarkouChris J. OatesVioleta Rayon-EstradaF. Nina PapavasiliouAnastasia PapavasiliouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dewi Harjanto Theodore Papamarkou Chris J. Oates Violeta Rayon-Estrada F. Nina Papavasiliou Anastasia Papavasiliou RNA editing generates cellular subsets with diverse sequence within populations
description	RNA editing rate detected from bulk RNA-seq data can vary widely. Here, by constructing a hierarchical Bayesian model, the authors report substantial variance in editing signatures detected by RNA-seq data from both single cells and a cognate bulk sample.
format	article
author	Dewi Harjanto Theodore Papamarkou Chris J. Oates Violeta Rayon-Estrada F. Nina Papavasiliou Anastasia Papavasiliou
author_facet	Dewi Harjanto Theodore Papamarkou Chris J. Oates Violeta Rayon-Estrada F. Nina Papavasiliou Anastasia Papavasiliou
author_sort	Dewi Harjanto
title	RNA editing generates cellular subsets with diverse sequence within populations
title_short	RNA editing generates cellular subsets with diverse sequence within populations
title_full	RNA editing generates cellular subsets with diverse sequence within populations
title_fullStr	RNA editing generates cellular subsets with diverse sequence within populations
title_full_unstemmed	RNA editing generates cellular subsets with diverse sequence within populations
title_sort	rna editing generates cellular subsets with diverse sequence within populations
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/39669e9caefe42a893d07c69afbb336f
work_keys_str_mv	AT dewiharjanto rnaeditinggeneratescellularsubsetswithdiversesequencewithinpopulations AT theodorepapamarkou rnaeditinggeneratescellularsubsetswithdiversesequencewithinpopulations AT chrisjoates rnaeditinggeneratescellularsubsetswithdiversesequencewithinpopulations AT violetarayonestrada rnaeditinggeneratescellularsubsetswithdiversesequencewithinpopulations AT fninapapavasiliou rnaeditinggeneratescellularsubsetswithdiversesequencewithinpopulations AT anastasiapapavasiliou rnaeditinggeneratescellularsubsetswithdiversesequencewithinpopulations
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RNA editing generates cellular subsets with diverse sequence within populations

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