NEW PLAYERS IN ALTERED TOLERANCE TO THYROID GLAND ANTIGENS: AN IMMUNOPATHOGENESIS CONCEPT OF AUTOIMMUNE THYROID DISEASE (REVIEW)

Precise mechanisms of tolerance loss to thyroid auto-antigens are still largely unknown, thus preventing further elucidation of key pathogenetic stages in autoimmune diseases affecting thyroid gland, and, therefore, to identify target pathways for treatment of these disorders. Detailed studies on th...

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Autores principales:	V. V. Zdor, E. V. Markelova, B. I. Geltser
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2016
Materias:	self-antigens tolerance thyrocytes autoantibodies mast cell cytokines Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/397475bfb6074fe69c7748bd1359f70c
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id	oai:doaj.org-article:397475bfb6074fe69c7748bd1359f70c
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spelling	oai:doaj.org-article:397475bfb6074fe69c7748bd1359f70c2021-11-18T08:03:45ZNEW PLAYERS IN ALTERED TOLERANCE TO THYROID GLAND ANTIGENS: AN IMMUNOPATHOGENESIS CONCEPT OF AUTOIMMUNE THYROID DISEASE (REVIEW)1563-06252313-741X10.15789/1563-0625-2016-3-209-220https://doaj.org/article/397475bfb6074fe69c7748bd1359f70c2016-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/1033https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XPrecise mechanisms of tolerance loss to thyroid auto-antigens are still largely unknown, thus preventing further elucidation of key pathogenetic stages in autoimmune diseases affecting thyroid gland, and, therefore, to identify target pathways for treatment of these disorders. Detailed studies on the role of innate and adaptive immune cells in disturbed tolerance to autoantigens specific for thyroid gland in Graves’ disease and autoimmune Hashimoto’s thyroiditis have revealed and provided a number of theoretical foundations for arrangement of clinical immunological monitoring and forecasting of these diseases in a long-term prospective.V. V. ZdorE. V. MarkelovaB. I. GeltserSPb RAACIarticleself-antigenstolerancethyrocytesautoantibodiesmast cellcytokinesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 18, Iss 3, Pp 209-220 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	self-antigens tolerance thyrocytes autoantibodies mast cell cytokines Immunologic diseases. Allergy RC581-607
spellingShingle	self-antigens tolerance thyrocytes autoantibodies mast cell cytokines Immunologic diseases. Allergy RC581-607 V. V. Zdor E. V. Markelova B. I. Geltser NEW PLAYERS IN ALTERED TOLERANCE TO THYROID GLAND ANTIGENS: AN IMMUNOPATHOGENESIS CONCEPT OF AUTOIMMUNE THYROID DISEASE (REVIEW)
description	Precise mechanisms of tolerance loss to thyroid auto-antigens are still largely unknown, thus preventing further elucidation of key pathogenetic stages in autoimmune diseases affecting thyroid gland, and, therefore, to identify target pathways for treatment of these disorders. Detailed studies on the role of innate and adaptive immune cells in disturbed tolerance to autoantigens specific for thyroid gland in Graves’ disease and autoimmune Hashimoto’s thyroiditis have revealed and provided a number of theoretical foundations for arrangement of clinical immunological monitoring and forecasting of these diseases in a long-term prospective.
format	article
author	V. V. Zdor E. V. Markelova B. I. Geltser
author_facet	V. V. Zdor E. V. Markelova B. I. Geltser
author_sort	V. V. Zdor
title	NEW PLAYERS IN ALTERED TOLERANCE TO THYROID GLAND ANTIGENS: AN IMMUNOPATHOGENESIS CONCEPT OF AUTOIMMUNE THYROID DISEASE (REVIEW)
title_short	NEW PLAYERS IN ALTERED TOLERANCE TO THYROID GLAND ANTIGENS: AN IMMUNOPATHOGENESIS CONCEPT OF AUTOIMMUNE THYROID DISEASE (REVIEW)
title_full	NEW PLAYERS IN ALTERED TOLERANCE TO THYROID GLAND ANTIGENS: AN IMMUNOPATHOGENESIS CONCEPT OF AUTOIMMUNE THYROID DISEASE (REVIEW)
title_fullStr	NEW PLAYERS IN ALTERED TOLERANCE TO THYROID GLAND ANTIGENS: AN IMMUNOPATHOGENESIS CONCEPT OF AUTOIMMUNE THYROID DISEASE (REVIEW)
title_full_unstemmed	NEW PLAYERS IN ALTERED TOLERANCE TO THYROID GLAND ANTIGENS: AN IMMUNOPATHOGENESIS CONCEPT OF AUTOIMMUNE THYROID DISEASE (REVIEW)
title_sort	new players in altered tolerance to thyroid gland antigens: an immunopathogenesis concept of autoimmune thyroid disease (review)
publisher	SPb RAACI
publishDate	2016
url	https://doaj.org/article/397475bfb6074fe69c7748bd1359f70c
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_version_	1718422409852223488

NEW PLAYERS IN ALTERED TOLERANCE TO THYROID GLAND ANTIGENS: AN IMMUNOPATHOGENESIS CONCEPT OF AUTOIMMUNE THYROID DISEASE (REVIEW)

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