Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer

Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer

Group I Paks, like Pak1, are required for the activation of several key oncogenic signaling pathways. Here the authors study an inducible peptide mimicking the auto-inhibitory domain of Pak1 and show promising anti-tumor effects in a mouse model of colorectal cancer.

Guardado en:
Detalles Bibliográficos
Autores principales: H. Y. Chow, B. Dong, C. A. Valencia, C. T. Zeng, J. N. Koch, T. Y. Prudnikova, J. Chernoff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/3974d458c1394ee9a963760e6ec8129f
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares