Engineering fungal de novo fatty acid synthesis for short chain fatty acid production
The production of short chain fatty acids by microorganisms has numerous industrial and biofuel applications. Here the authors reprogrammeS. cerevisiaefatty acid synthase with five mutations to produce C6- and C8-fatty acids and identify thioesterases responsible for hydrolysis of short chain acyl-C...
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Nature Portfolio
2017
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oai:doaj.org-article:397951b7b0c24bef91a61ee9510dd0752021-12-02T17:06:19ZEngineering fungal de novo fatty acid synthesis for short chain fatty acid production10.1038/ncomms146502041-1723https://doaj.org/article/397951b7b0c24bef91a61ee9510dd0752017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14650https://doaj.org/toc/2041-1723The production of short chain fatty acids by microorganisms has numerous industrial and biofuel applications. Here the authors reprogrammeS. cerevisiaefatty acid synthase with five mutations to produce C6- and C8-fatty acids and identify thioesterases responsible for hydrolysis of short chain acyl-CoA hydrolysis.Jan GajewskiRenata PavlovicManuel FischerEckhard BolesMartin GriningerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017) |
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Science Q Jan Gajewski Renata Pavlovic Manuel Fischer Eckhard Boles Martin Grininger Engineering fungal de novo fatty acid synthesis for short chain fatty acid production |
description |
The production of short chain fatty acids by microorganisms has numerous industrial and biofuel applications. Here the authors reprogrammeS. cerevisiaefatty acid synthase with five mutations to produce C6- and C8-fatty acids and identify thioesterases responsible for hydrolysis of short chain acyl-CoA hydrolysis. |
format |
article |
author |
Jan Gajewski Renata Pavlovic Manuel Fischer Eckhard Boles Martin Grininger |
author_facet |
Jan Gajewski Renata Pavlovic Manuel Fischer Eckhard Boles Martin Grininger |
author_sort |
Jan Gajewski |
title |
Engineering fungal de novo fatty acid synthesis for short chain fatty acid production |
title_short |
Engineering fungal de novo fatty acid synthesis for short chain fatty acid production |
title_full |
Engineering fungal de novo fatty acid synthesis for short chain fatty acid production |
title_fullStr |
Engineering fungal de novo fatty acid synthesis for short chain fatty acid production |
title_full_unstemmed |
Engineering fungal de novo fatty acid synthesis for short chain fatty acid production |
title_sort |
engineering fungal de novo fatty acid synthesis for short chain fatty acid production |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/397951b7b0c24bef91a61ee9510dd075 |
work_keys_str_mv |
AT jangajewski engineeringfungaldenovofattyacidsynthesisforshortchainfattyacidproduction AT renatapavlovic engineeringfungaldenovofattyacidsynthesisforshortchainfattyacidproduction AT manuelfischer engineeringfungaldenovofattyacidsynthesisforshortchainfattyacidproduction AT eckhardboles engineeringfungaldenovofattyacidsynthesisforshortchainfattyacidproduction AT martingrininger engineeringfungaldenovofattyacidsynthesisforshortchainfattyacidproduction |
_version_ |
1718381666040283136 |