Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis

Abstract Inflammation, vascular smooth muscle cell apoptosis and oxidative stress are believed to play important roles in abdominal aortic aneurysm (AAA) pathogenesis. Human kallistatin (KAL; gene SERPINA4) is a serine proteinase inhibitor previously shown to inhibit inflammation, apoptosis and oxid...

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Autores principales: Smriti Murali Krishna, Jiaze Li, Yutang Wang, Corey S. Moran, Alexandra Trollope, Pacific Huynh, Roby Jose, Erik Biros, Jianxing Ma, Jonathan Golledge
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/397c6e28517446e49fbf89fa1ca7b4c8
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