VERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES

Objective: To assess the vertical transmission of Corona Virus disease (COVID-19) from infected pregnant mothers to neonates. Study Design: Cross sectional study. Place and Duration of Study: Department of Obstetrics and Gynaecology, Pak Emirates Military Hospital Rawalpindi, from May 2020 to Jun 20...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Abeera Choudry, Jehan Ara Rafiq Baig, Zainab Abbas Mirza, Munawar Jannat, Zeeshan Ahmed, Mobeen Shafique
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	corona virus disease-19 (covid-19) vertical transmission immunoglobulins pregnancy reverse transcriptase polymerase chain reaction (rt-pcr) Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/398160a776f847b9bb4387191bba6350
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:398160a776f847b9bb4387191bba6350
record_format	dspace
spelling	oai:doaj.org-article:398160a776f847b9bb4387191bba63502021-12-02T17:19:47ZVERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES0030-96482411-8842https://doaj.org/article/398160a776f847b9bb4387191bba63502020-09-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5225https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess the vertical transmission of Corona Virus disease (COVID-19) from infected pregnant mothers to neonates. Study Design: Cross sectional study. Place and Duration of Study: Department of Obstetrics and Gynaecology, Pak Emirates Military Hospital Rawalpindi, from May 2020 to Jun 2020. Methodology: A total of 90 pregnant patients reported in Pak Emirates Military Hospital during the pandemic of COVID-19 with COVID-19 test positive from 01 May 2020 to 30 June 2020. Diagnosis was confirmed with reverse transcriptase polymerase chain reaction (RT- PCR) of nasal and throat swabs. Clinical, analytical, laboratory and radiographic findings were then recorded. The (RT-PCR) for COVID-19 of all the babies who were delivered to these mothers was also done on throat and nasal swabs. The neonatal blood was also sent for serology (IgM/IgG). Results: Out of 90 patients studied, 46 were delivered either through a Caesarean section or by vaginal delivery. The patients were categorized as asymptomatic 51 (55.66%) and symptomatic 39 (43.33%). Out of those symptomatic, patients with mild to moderate disease were 33 (84.61%), patients with severe disease 05 (12.82%) and critically ill patient was 01 (2.56%). All the patients who delivered were COVID-19 test positive at the time of delivery and later when the babies of all these mothers were tested, they were all found to be COVID-19 negative on RT-PCR and no immunoglobulins were found in the serum of these neonates. The possibility for transplacental transmission could only be checked by these two methods (RT-PCR and Serology) since RT-PCR of amniotic fluid, high vaginal swab and breast milk was not available. Conclusion: In our study we did not find any evidence of vertical transmission of corona virus disease -19 (COVID-19) from infected pregnant mothers to neonates.Abeera ChoudryJehan Ara Rafiq BaigZainab Abbas MirzaMunawar JannatZeeshan AhmedMobeen ShafiqueArmy Medical College Rawalpindiarticlecorona virus disease-19 (covid-19) vertical transmissionimmunoglobulinspregnancyreverse transcriptase polymerase chain reaction (rt-pcr)MedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 2, Pp 444-449 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	corona virus disease-19 (covid-19) vertical transmission immunoglobulins pregnancy reverse transcriptase polymerase chain reaction (rt-pcr) Medicine R Medicine (General) R5-920
spellingShingle	corona virus disease-19 (covid-19) vertical transmission immunoglobulins pregnancy reverse transcriptase polymerase chain reaction (rt-pcr) Medicine R Medicine (General) R5-920 Abeera Choudry Jehan Ara Rafiq Baig Zainab Abbas Mirza Munawar Jannat Zeeshan Ahmed Mobeen Shafique VERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES
description	Objective: To assess the vertical transmission of Corona Virus disease (COVID-19) from infected pregnant mothers to neonates. Study Design: Cross sectional study. Place and Duration of Study: Department of Obstetrics and Gynaecology, Pak Emirates Military Hospital Rawalpindi, from May 2020 to Jun 2020. Methodology: A total of 90 pregnant patients reported in Pak Emirates Military Hospital during the pandemic of COVID-19 with COVID-19 test positive from 01 May 2020 to 30 June 2020. Diagnosis was confirmed with reverse transcriptase polymerase chain reaction (RT- PCR) of nasal and throat swabs. Clinical, analytical, laboratory and radiographic findings were then recorded. The (RT-PCR) for COVID-19 of all the babies who were delivered to these mothers was also done on throat and nasal swabs. The neonatal blood was also sent for serology (IgM/IgG). Results: Out of 90 patients studied, 46 were delivered either through a Caesarean section or by vaginal delivery. The patients were categorized as asymptomatic 51 (55.66%) and symptomatic 39 (43.33%). Out of those symptomatic, patients with mild to moderate disease were 33 (84.61%), patients with severe disease 05 (12.82%) and critically ill patient was 01 (2.56%). All the patients who delivered were COVID-19 test positive at the time of delivery and later when the babies of all these mothers were tested, they were all found to be COVID-19 negative on RT-PCR and no immunoglobulins were found in the serum of these neonates. The possibility for transplacental transmission could only be checked by these two methods (RT-PCR and Serology) since RT-PCR of amniotic fluid, high vaginal swab and breast milk was not available. Conclusion: In our study we did not find any evidence of vertical transmission of corona virus disease -19 (COVID-19) from infected pregnant mothers to neonates.
format	article
author	Abeera Choudry Jehan Ara Rafiq Baig Zainab Abbas Mirza Munawar Jannat Zeeshan Ahmed Mobeen Shafique
author_facet	Abeera Choudry Jehan Ara Rafiq Baig Zainab Abbas Mirza Munawar Jannat Zeeshan Ahmed Mobeen Shafique
author_sort	Abeera Choudry
title	VERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES
title_short	VERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES
title_full	VERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES
title_fullStr	VERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES
title_full_unstemmed	VERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES
title_sort	vertical transmission of corona virus disease-19 (covid-19) from infected pregnant mothers to neonates
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doaj.org/article/398160a776f847b9bb4387191bba6350
work_keys_str_mv	AT abeerachoudry verticaltransmissionofcoronavirusdisease19covid19frominfectedpregnantmotherstoneonates AT jehanararafiqbaig verticaltransmissionofcoronavirusdisease19covid19frominfectedpregnantmotherstoneonates AT zainababbasmirza verticaltransmissionofcoronavirusdisease19covid19frominfectedpregnantmotherstoneonates AT munawarjannat verticaltransmissionofcoronavirusdisease19covid19frominfectedpregnantmotherstoneonates AT zeeshanahmed verticaltransmissionofcoronavirusdisease19covid19frominfectedpregnantmotherstoneonates AT mobeenshafique verticaltransmissionofcoronavirusdisease19covid19frominfectedpregnantmotherstoneonates
_version_	1718381020141584384

VERTICAL TRANSMISSION OF CORONA VIRUS DISEASE-19 (COVID-19) FROM INFECTED PREGNANT MOTHERS TO NEONATES

Ejemplares similares