Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis

Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis

Meningitis is a severe form of invasive pneumococcal disease (IPD). To study the contribution of bacterial genomic variation, here Li et al. perform whole genome sequencing of pneumococcal isolates from IPD patients and identify an association for higher risk of meningitis with a pbp1bA641C variant

Guardado en:
Detalles Bibliográficos
Autores principales: Yuan Li, Benjamin J. Metcalf, Sopio Chochua, Zhongya Li, Hollis Walker, Theresa Tran, Paulina A. Hawkins, Ryan Gierke, Tamara Pilishvili, Lesley McGee, Bernard W. Beall
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/3981a36b97a44b1f8420f9609ccbf4bd
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Meningitis is a severe form of invasive pneumococcal disease (IPD). To study the contribution of bacterial genomic variation, here Li et al. perform whole genome sequencing of pneumococcal isolates from IPD patients and identify an association for higher risk of meningitis with a pbp1bA641C variant

Ejemplares similares