Calcium Binding Proteins]

ABSTRACTCalcium ions are essentail for some of the cellular functions, including musclecontraction, adhesion, secretion, motility, growth, differentiation, gene expression,and cell death. The change in calcium concentration is transmitted as a signal ofthe intracellular second messenger. Calcium bin...

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Autores principales:	Berivan Tandoğan, N. Nuray Ulusu
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2006
Materias:	Calcium binding proteins calmodulin S100 protein family annexins Biochemistry QD415-436
Acceso en línea:	https://doaj.org/article/398b200207f94e1faf14e44bdd47b274
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id	oai:doaj.org-article:398b200207f94e1faf14e44bdd47b274
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spelling	oai:doaj.org-article:398b200207f94e1faf14e44bdd47b2742021-12-02T13:09:59ZCalcium Binding Proteins]0250-46851303-829Xhttps://doaj.org/article/398b200207f94e1faf14e44bdd47b2742006-03-01T00:00:00Zhttp://www.turkjbiochem.com/2006/036_040.pdfhttps://doaj.org/toc/0250-4685https://doaj.org/toc/1303-829XABSTRACTCalcium ions are essentail for some of the cellular functions, including musclecontraction, adhesion, secretion, motility, growth, differentiation, gene expression,and cell death. The change in calcium concentration is transmitted as a signal ofthe intracellular second messenger. Calcium binding proteins are the mediators ofthe signal, and play pivotal roles in the many cellular processes through a varietyof different mechanisms. Calcium binding proteins are also an important molecularchaperones involved in the protein synthesis within secretory pathways. Theirmajor role is assumed to be buffering, transport of calcium, and regulation of variousenzyme systems. Calcium binding proteins have remarkable sequence homologyand structural similarity, yet they function in a wide range of biologicalprocesses. Several important disease states; hypertension, heart disease, diabetes,manic depression, Alzheimer’s disease may result from abnormal remodeling ofcalcium binding proteins. It has been found that several calcium binding proteinshave important roles in cell survival and apoptosis pathways and may also promotecancer progression. Because of the levels of calcium binding protein expressionhas changed in different stages and types of cancer, these proteins can be used ascancer markers.Berivan TandoğanN. Nuray UlusuDe GruyterarticleCalcium binding proteinscalmodulinS100 protein familyannexinsBiochemistryQD415-436ENTürk Biyokimya Dergisi, Vol 31, Iss 1, Pp 36-40 (2006)
institution	DOAJ
collection	DOAJ
language	EN
topic	Calcium binding proteins calmodulin S100 protein family annexins Biochemistry QD415-436
spellingShingle	Calcium binding proteins calmodulin S100 protein family annexins Biochemistry QD415-436 Berivan Tandoğan N. Nuray Ulusu Calcium Binding Proteins]
description	ABSTRACTCalcium ions are essentail for some of the cellular functions, including musclecontraction, adhesion, secretion, motility, growth, differentiation, gene expression,and cell death. The change in calcium concentration is transmitted as a signal ofthe intracellular second messenger. Calcium binding proteins are the mediators ofthe signal, and play pivotal roles in the many cellular processes through a varietyof different mechanisms. Calcium binding proteins are also an important molecularchaperones involved in the protein synthesis within secretory pathways. Theirmajor role is assumed to be buffering, transport of calcium, and regulation of variousenzyme systems. Calcium binding proteins have remarkable sequence homologyand structural similarity, yet they function in a wide range of biologicalprocesses. Several important disease states; hypertension, heart disease, diabetes,manic depression, Alzheimer’s disease may result from abnormal remodeling ofcalcium binding proteins. It has been found that several calcium binding proteinshave important roles in cell survival and apoptosis pathways and may also promotecancer progression. Because of the levels of calcium binding protein expressionhas changed in different stages and types of cancer, these proteins can be used ascancer markers.
format	article
author	Berivan Tandoğan N. Nuray Ulusu
author_facet	Berivan Tandoğan N. Nuray Ulusu
author_sort	Berivan Tandoğan
title	Calcium Binding Proteins]
title_short	Calcium Binding Proteins]
title_full	Calcium Binding Proteins]
title_fullStr	Calcium Binding Proteins]
title_full_unstemmed	Calcium Binding Proteins]
title_sort	calcium binding proteins]
publisher	De Gruyter
publishDate	2006
url	https://doaj.org/article/398b200207f94e1faf14e44bdd47b274
work_keys_str_mv	AT berivantandogan calciumbindingproteins AT nnurayulusu calciumbindingproteins
_version_	1718393440729825280

Calcium Binding Proteins]

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